AIMC Topic: United Kingdom

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Deep Learning-Based Automated Abdominal Organ Segmentation in the UK Biobank and German National Cohort Magnetic Resonance Imaging Studies.

Investigative radiology
PURPOSE: The aims of this study were to train and evaluate deep learning models for automated segmentation of abdominal organs in whole-body magnetic resonance (MR) images from the UK Biobank (UKBB) and German National Cohort (GNC) MR imaging studies...

Machine Learning Algorithms Reveals Country-Specific Metagenomic Taxa from American Gut Project Data.

Studies in health technology and informatics
In recent years, microbiota has become an increasingly relevant factor for the understanding and potential treatment of diseases. In this work, based on the data reported by the largest study of microbioma in the world, a classification model has bee...

Deep-learning-based cardiovascular risk stratification using coronary artery calcium scores predicted from retinal photographs.

The Lancet. Digital health
BACKGROUND: Coronary artery calcium (CAC) score is a clinically validated marker of cardiovascular disease risk. We developed and validated a novel cardiovascular risk stratification system based on deep-learning-predicted CAC from retinal photograph...

A UK-Wide Study Employing Natural Language Processing to Determine What Matters to People about Brain Health to Improve Drug Development: The Electronic Person-Specific Outcome Measure (ePSOM) Programme.

The journal of prevention of Alzheimer's disease
BACKGROUND: It is important to use outcome measures for novel interventions in Alzheimer's disease (AD) that capture the research participants' views of effectiveness. The electronic Person-Specific Outcome Measure (ePSOM) development programme is un...

Prediction of systemic biomarkers from retinal photographs: development and validation of deep-learning algorithms.

The Lancet. Digital health
BACKGROUND: The application of deep learning to retinal photographs has yielded promising results in predicting age, sex, blood pressure, and haematological parameters. However, the broader applicability of retinal photograph-based deep learning for ...

A NICE perspective on computable biomedical knowledge.

BMJ health & care informatics
INTRODUCTION: The National Institute for Health and Care Excellence (NICE) plays a central role in the NHS. We distill knowledge of best practice from the best available sources of evidence and share this across the health and care system, typically ...

HDR UK supporting mobilising computable biomedical knowledge in the UK.

BMJ health & care informatics
Computable biomedical knowledge (CBK) represents an evolving area of health informatics, with potential for rapid translational patient benefit. Health Data Research UK (HDR UK) is the national Institute for Health Data Science, whose aim is to unite...

Natural language processing for structuring clinical text data on depression using UK-CRIS.

Evidence-based mental health
BACKGROUND: Utilisation of routinely collected electronic health records from secondary care offers unprecedented possibilities for medical science research but can also present difficulties. One key issue is that medical information is presented as ...

The Genome3D Consortium for Structural Annotations of Selected Model Organisms.

Methods in molecular biology (Clifton, N.J.)
Genome3D consortium is a collaborative project involving protein structure prediction and annotation resources developed by six world-leading structural bioinformatics groups, based in the United Kingdom (namely Blundell, Murzin, Gough, Sternberg, Or...