AIMC Topic: United Kingdom
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Transfer Learning Prediction of Early Exposures and Genetic Risk Score on Adult Obesity in Two Minority Cohorts.
Prevention science : the official journal of the Society for Prevention Research
Feb 6, 2025
Due to ethnic heterogeneity in genetic architecture, genetic risk score (GRS) constructed within the European population generally possesses poor portability in underrepresented non-European populations, but substantial genetic similarity exists acro...
Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study.
PLoS medicine
Feb 4, 2025
BACKGROUND: Preeclampsia is a potentially life-threatening pregnancy complication. Among women whose pregnancies are complicated by preeclampsia, the Preeclampsia Integrated Estimate of RiSk (PIERS) models (i.e., the PIERS Machine Learning [PIERS-ML]...
UK Biobank MRI data can power the development of generalizable brain clocks: A study of standard ML/DL methodologies and performance analysis on external databases.
NeuroImage
Jan 30, 2025
In this study, we present a comprehensive pipeline to train and compare a broad spectrum of machine learning and deep learning brain clocks, integrating diverse preprocessing strategies and correction terms. Our analysis also includes established met...
Incidence and Predictors of Acute Kidney Injury Following Advanced Ovarian Cancer Cytoreduction at a Tertiary UK Centre: An Exploratory Analysis and Insights from Explainable Artificial Intelligence.
Current oncology (Toronto, Ont.)
Jan 28, 2025
BACKGROUND/OBJECTIVES: The incidence of acute kidney injury (AKI) following advanced epithelial ovarian cancer (EOC) surgery has not been extensively studied. This study aimed to investigate the incidence of AKI and identify preoperative and intraope...
Artificial intelligence assisted risk prediction in organ transplantation: a UK Live-Donor Kidney Transplant Outcome Prediction tool.
Renal failure
Jan 21, 2025
Predicting the outcome of a kidney transplant involving a living donor advances donor decision-making donors for clinicians and patients. However, the discriminative or calibration capacity of the currently employed models are limited. We set out to...
Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom.
American journal of ophthalmology
Jan 13, 2025
PURPOSE: A previously developed machine-learning approach with Kalman filtering technology accurately predicted the disease trajectory for patients with various glaucoma types and severities using clinical trial data. This study assesses performance ...
Machine learning in the prediction of human wellbeing.
Scientific reports
Jan 10, 2025
Subjective wellbeing data are increasingly used across the social sciences. Yet, despite the widespread use of such data, the predictive power of approaches commonly used to model wellbeing is only limited. In response, we here use tree-based Machine...
Clinicians' perspectives on the use of artificial intelligence to triage MRI brain scans.
European journal of radiology
Jan 6, 2025
Artificial intelligence (AI) tools can triage radiology scans to streamline the patient pathway and also relieve clinician workload. Validated AI tools can mitigate the delays in reporting scans by flagging time-sensitive and actionable findings. In ...
Evaluating the pathological and clinical implications of errors made by an artificial intelligence colon biopsy screening tool.
BMJ open gastroenterology
Jan 6, 2025
OBJECTIVE: Artificial intelligence (AI) tools for histological diagnosis offer great potential to healthcare, yet failure to understand their clinical context is delaying adoption. IGUANA (Interpretable Gland-Graphs using a Neural Aggregator) is an A...
Deep learning and genome-wide association meta-analyses of bone marrow adiposity in the UK Biobank.
Nature communications
Jan 2, 2025
Bone marrow adipose tissue is a distinct adipose subtype comprising more than 10% of fat mass in healthy humans. However, the functions and pathophysiological correlates of this tissue are unclear, and its genetic determinants remain unknown. Here, w...
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