AIMC Topic: United Kingdom

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Addressing underestimation and explanation of retinal fundus photo-based cardiovascular disease risk score: Algorithm development and validation.

Computers in biology and medicine
OBJECTIVE: To resolve the underestimation problem and investigate the mechanism of the AI model which employed to predict cardiovascular disease (CVD) risk scores from retinal fundus photos.

An interpretable machine learning approach for detecting psoriatic arthritis in a UK primary care psoriasis cohort using electronic health records from the Clinical Practice Research Datalink.

Annals of the rheumatic diseases
OBJECTIVES: Develop an interpretable machine learning model to detect patients with newly diagnosed psoriatic arthritis (PsA) in a cohort of psoriasis patients and identify important clinical indicators of PsA in primary care.

AI-powered prostate cancer detection: a multi-centre, multi-scanner validation study.

European radiology
OBJECTIVES: Multi-centre, multi-vendor validation of artificial intelligence (AI) software to detect clinically significant prostate cancer (PCa) using multiparametric magnetic resonance imaging (MRI) is lacking. We compared a new AI solution, valida...

Estimation of Machine Learning-Based Models to Predict Dementia Risk in Patients With Atherosclerotic Cardiovascular Diseases: UK Biobank Study.

JMIR aging
BACKGROUND: The atherosclerotic cardiovascular disease (ASCVD) is associated with dementia. However, the risk factors of dementia in patients with ASCVD remain unclear, necessitating the development of accurate prediction models.

Histological proven AI performance in the UKLS CT lung cancer screening study: Potential for workload reduction.

European journal of cancer (Oxford, England : 1990)
PURPOSE: Artificial intelligence (AI) could reduce lung cancer screening computer tomography (CT)-reading workload if used as a first-reader, ruling-out negative CT-scans at baseline. Evidence is lacking to support AI performance when compared to gol...

RADEX: a rule-based clinical and radiology data extraction tool demonstrated on thyroid ultrasound reports.

European radiology
OBJECTIVES: Radiology reports contain valuable information for research and audits, but relevant details are often buried within free-text fields. This makes them challenging and time-consuming to extract for secondary analyses, including training ar...

Understanding the Engagement and Interaction of Superusers and Regular Users in UK Respiratory Online Health Communities: Deep Learning-Based Sentiment Analysis.

Journal of medical Internet research
BACKGROUND: Online health communities (OHCs) enable people with long-term conditions (LTCs) to exchange peer self-management experiential information, advice, and support. Engagement of "superusers," that is, highly active users, plays a key role in ...

Transfer Learning Prediction of Early Exposures and Genetic Risk Score on Adult Obesity in Two Minority Cohorts.

Prevention science : the official journal of the Society for Prevention Research
Due to ethnic heterogeneity in genetic architecture, genetic risk score (GRS) constructed within the European population generally possesses poor portability in underrepresented non-European populations, but substantial genetic similarity exists acro...

Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study.

PLoS medicine
BACKGROUND: Preeclampsia is a potentially life-threatening pregnancy complication. Among women whose pregnancies are complicated by preeclampsia, the Preeclampsia Integrated Estimate of RiSk (PIERS) models (i.e., the PIERS Machine Learning [PIERS-ML]...

UK Biobank MRI data can power the development of generalizable brain clocks: A study of standard ML/DL methodologies and performance analysis on external databases.

NeuroImage
In this study, we present a comprehensive pipeline to train and compare a broad spectrum of machine learning and deep learning brain clocks, integrating diverse preprocessing strategies and correction terms. Our analysis also includes established met...