AIMC Topic: Uric Acid
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The potential impact of the hypovitaminosis D on metabolic complications in obese adolescents - Preliminary results.
Annals of agricultural and environmental medicine : AAEM
May 11, 2017
INTRODUCTION AND OBJECTIVE: Vitamin D deficiency is common in obesity; however, its contribution in the development of metabolic complications remains uncertain. The aim of the study was to examine the relationships between vitamin D status and metab...
[Association between gut microbiota and hyperuricemia: insights into innovative therapeutic strategies].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Jun 25, 2025
Uric acid (UA) is the final metabolite of purines in the human body. An imbalance in UA production and excretion that disrupts homeostasis leads to elevated blood UA levels and the development of hyperuricemia (HUA). Approximately one-third of UA is ...
Deep learning reconstruction enhances tophus detection in a dual-energy CT phantom study.
Scientific reports
May 28, 2025
This study aimed to compare two deep learning reconstruction (DLR) techniques (AiCE mild; AiCE strong) with two established methods-iterative reconstruction (IR) and filtered back projection (FBP)-for the detection of monosodium urate (MSU) in dual-e...
An artificial intelligence-based gout management system reduced chronic kidney disease incident and improved target serum urate achievement.
Rheumatology (Oxford, England)
May 1, 2025
OBJECTIVES: Stage ≥3 chronic kidney disease (CKD) affects ∼25% of people with gout. The effects of urate-lowering therapy (ULT) on CKD incidence and progression have remained inconclusive. Here, we assessed the impact of a gout ULT clinic interventio...
Exploring the Impact of PA and Sedentary Behavior on Gout Risk in Hyperuricemia: Insights From Machine Learning and SHAP Analysis.
International journal of rheumatic diseases
Apr 1, 2025
BACKGROUND: Individuals with hyperuricemia (HUA) are widely recognized as being at increased risk for gout. This study aimed to investigate how physical activity (PA) duration and sedentary duration impact gout risk in individuals with HUA and to dev...
An objective diagnosis of gout and calcium pyrophosphate deposition disease with machine learning of Raman spectra acquired in a point-of-care setting.
Rheumatology (Oxford, England)
Apr 1, 2025
OBJECTIVE: Raman spectroscopy is proposed as a next-generation method for the identification of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluid. As the interpretation of Raman spectra requires specific expertise, the...
Deep Learning for the Study of Urinary Stone Composition from Computed Tomography Images.
Archivos espanoles de urologia
Nov 1, 2024
OBJECTIVES: Urinary stones composed of uric acid can be treated with medicine. Computed tomography (CT) can diagnose urinary stone disease, but it is difficult to predict the type of uric stones. This study aims to develop a method to distinguish pur...
A machine learning-based prediction model for gout in hyperuricemics: a nationwide cohort study.
Rheumatology (Oxford, England)
Sep 1, 2024
OBJECTIVE: To develop a machine learning-based prediction model for identifying hyperuricemic participants at risk of developing gout.
Predictive markers of depression in hypertension.
Medicine
Aug 1, 2018
Hypertension and depression, as 2 major public health issues, are closely related. For patients having hypertension, in particular, depression is a risk factor for mortality and jeopardizes their wellbeing. The aim of the study is to apply support ve...
Benefits of Allopurinol Treatment on Blood Pressure and Renal Function in Patients with Early Stage of Chronic Kidney Disease.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet
Dec 1, 2015
BACKGROUND: Hyperuricemia has been associated with increased risk of endothelial dysfunction, cardiovascular, and renal disease. Allopurinol is a potent xanthine oxidase inhibitor used in hyperuricemic patients. It has been shown to decrease cardiova...
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