AIMC Topic: Adult

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Mixed effect machine learning: A framework for predicting longitudinal change in hemoglobin A1c.

Journal of biomedical informatics
Accurate and reliable prediction of clinical progression over time has the potential to improve the outcomes of chronic disease. The classical approach to analyzing longitudinal data is to use (generalized) linear mixed-effect models (GLMM). However,...

Development and Validation of a Deep Learning System for Staging Liver Fibrosis by Using Contrast Agent-enhanced CT Images in the Liver.

Radiology
Purpose To develop and validate a deep learning system (DLS) for staging liver fibrosis by using CT images in the liver. Materials and Methods DLS for CT-based staging of liver fibrosis was created by using a development data set that included portal...

A comparative study of logistic regression based machine learning techniques for prediction of early virological suppression in antiretroviral initiating HIV patients.

BMC medical informatics and decision making
BACKGROUND: Treatment with effective antiretroviral therapy (ART) lowers morbidity and mortality among HIV positive individuals. Effective highly active antiretroviral therapy (HAART) should lead to undetectable viral load within 6 months of initiati...

Personalized prediction model for seizure-free epilepsy with levetiracetam therapy: a retrospective data analysis using support vector machine.

British journal of clinical pharmacology
AIMS: To predict the probability of a seizure-free (SF) state in patients with epilepsy (PWEs) after treatment with levetiracetam and to identify the clinical and electroencephalographic (EEG) factors that affect outcomes.

A kernel machine method for detecting higher order interactions in multimodal datasets: Application to schizophrenia.

Journal of neuroscience methods
BACKGROUND: Technological advances are enabling us to collect multimodal datasets at an increasing depth and resolution while with decreasing labors. Understanding complex interactions among multimodal datasets, however, is challenging.

Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease.

PloS one
Prognostic modelling is important in clinical practice and epidemiology for patient management and research. Electronic health records (EHR) provide large quantities of data for such models, but conventional epidemiological approaches require signifi...

Decision Support System for Seizure Onset Zone Localization Based on Channel Ranking and High-Frequency EEG Activity.

IEEE journal of biomedical and health informatics
Interictal high-frequency oscillations (HFO) are a promising biomarker that can help define the seizure onset zone (SOZ) and predict the surgical outcome after the epilepsy surgery. The utility of HFO in planning the surgery, though, is unclear. Reas...

A Novel Extension to Fuzzy Connectivity for Body Composition Analysis: Applications in Thigh, Brain, and Whole Body Tissue Segmentation.

IEEE transactions on bio-medical engineering
Magnetic resonance imaging (MRI) is the non-invasive modality of choice for body tissue composition analysis due to its excellent soft-tissue contrast and lack of ionizing radiation. However, quantification of body composition requires an accurate se...