AIMC Topic: Adult

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Unsupervised Clustering of Missense Variants in HNF1A Using Multidimensional Functional Data Aids Clinical Interpretation.

American journal of human genetics
Exome sequencing in diabetes presents a diagnostic challenge because depending on frequency, functional impact, and genomic and environmental contexts, HNF1A variants can cause maturity-onset diabetes of the young (MODY), increase type 2 diabetes ris...

MRI-visible dilated perivascular spaces in healthy young adults: A twin heritability study.

Human brain mapping
We investigated the narrow-sense heritability of MRI-visible dilated perivascular spaces (dPVS) in healthy young adult twins and nontwin siblings (138 monozygotic, 79 dizygotic twin pairs, and 133 nontwin sibling pairs; 28.7 ± 3.6 years) from the Hum...

Radiomic Model for Distinguishing Dissecting Aneurysms from Complicated Saccular Aneurysms on high-Resolution Magnetic Resonance Imaging.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
OBJECTIVE: To build radiomic model in differentiating dissecting aneurysm (DA) from complicated saccular aneurysm (SA) based on high-resolution magnetic resonance imaging (HR-MRI) through machine-learning algorithm.

Image denoising by transfer learning of generative adversarial network for dental CT.

Biomedical physics & engineering express
The successful development of the image denoising techniques for low-dose computed tomography (LDCT) was largely owing to the public-domain availability of spatially-aligned high- and low-dose CT image pairs. Even though low-dose CT scans are also hi...

Development, implementation, and prospective validation of a model to predict 60-day end-of-life in hospitalized adults upon admission at three sites.

BMC medical informatics and decision making
BACKGROUND: Automated systems that use machine learning to estimate a patient's risk of death are being developed to influence care. There remains sparse transparent reporting of model generalizability in different subpopulations especially for imple...

fMRI volume classification using a 3D convolutional neural network robust to shifted and scaled neuronal activations.

NeuroImage
Deep-learning methods based on deep neural networks (DNNs) have recently been successfully utilized in the analysis of neuroimaging data. A convolutional neural network (CNN) is a type of DNN that employs a convolution kernel that covers a local area...

Machine-Learning Analysis of Voice Samples Recorded through Smartphones: The Combined Effect of Ageing and Gender.

Sensors (Basel, Switzerland)
BACKGROUND: Experimental studies using qualitative or quantitative analysis have demonstrated that the human voice progressively worsens with ageing. These studies, however, have mostly focused on specific voice features without examining their dynam...

Which Visual Modality Is Important When Judging the Naturalness of the Agent (Artificial Versus Human Intelligence) Providing Recommendations in the Symbolic Consumption Context?

Sensors (Basel, Switzerland)
This study aimed to explore how the type and visual modality of a recommendation agent's identity affect male university students' (1) self-reported responses to agent-recommended symbolic brand in evaluating the naturalness of virtual agents, human,...