AIMC Topic: Aged, 80 and over

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Predicting fracture toughness of human cortical bone from donors with and without type 2 diabetes using Raman spectroscopy and machine learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Type 2 diabetes mellitus (T2DM) is associated with increased skeletal fragility, yet standard clinical assessments often fail to detect diabetes-induced changes in bone quality. Raman spectroscopy (RS), a label-free and non-destructive technique, off...

Multimodal anti fraud education improves cognitive emotional and behavioral engagement in older adults.

Scientific reports
This study examines the differential effectiveness of video-based versus text-based anti-fraud educational interventions in improving cognitive comprehension, emotional engagement, and behavioral intentions among older adults. Using a stratified samp...

AI-driven fusion of multimodal data for Alzheimer's disease biomarker assessment.

Nature communications
Alzheimer's disease (AD) diagnosis hinges on detecting amyloid beta (Aβ) plaques and neurofibrillary tau (τ) tangles, typically assessed using PET imaging. While accurate, these modalities are expensive and not widely accessible, limiting their utili...

Machine learning based analysis of leucocyte cell population data by Sysmex XN series hematology analyzer for the diagnosis of bacteremia.

Scientific reports
In clinical practice, early recognition of bacteremia leads to prognostic improvement. Recently, cell population data (CPD) from the Sysmex XN-series hematology analyzer has attracted attention as a new method for the early diagnosis of bacteremia, b...

Longitudinal structural MRI-based deep learning and radiomics features for predicting Alzheimer's disease progression.

Alzheimer's research & therapy
BACKGROUND: Alzheimer's disease (AD) is the principal cause of dementia and requires the early diagnosis of people with mild cognitive impairment (MCI) who are at high risk of progressing. Early diagnosis is imperative for optimizing clinical managem...

Developing an Equitable Machine Learning-Based Music Intervention for Older Adults At Risk for Alzheimer Disease: Protocol for Algorithm Development and Validation.

JMIR research protocols
BACKGROUND: Given the high prevalence and cost of Alzheimer disease (AD), it is crucial to develop equitable interventions to address lifestyle factors associated with AD incidence (eg, depression). While lifestyle interventions show promise for redu...

Alzheimer's disease risk prediction using machine learning for survival analysis with a comorbidity-based approach.

Scientific reports
Alzheimer's disease (AD) presents a pressing global health challenge, demanding improved strategies for early detection and understanding its progression. In this study, we address this need by employing survival analysis techniques to predict transi...

Machine learning-based predictive modeling of angina pectoris in an elderly community-dwelling population: Results from the PoCOsteo study.

PloS one
BACKGROUND: Angina pectoris, a comparatively common complaint among older adults, is a critical warning sign of underlying coronary heart disease. We aimed to develop machine learning-based models using multiple algorithms to predict and identify the...

Machine learning algorithms for risk factor selection with application to 60-day sepsis morbidity risk for a geriatric hip fracture cohort.

BMC geriatrics
BACKGROUND: Sepsis after hip fracture in elderly people is a risk factor for mortality. The purpose of this study was to screen for risk factors for 60-day sepsis morbidity after hip fracture and to establish a predictive model using various machine ...

Age-related variation in hemoglobin glycation index and stroke mortality: mediation and machine learning in a cohort study.

Scientific reports
To investigate the associations between both age and the hemoglobin glycation index (HGI) and the 30-day and 1-year mortality in ischemic stroke (IS) patients and to analyze the mediating effect of the HGI on the relationship between age and mortalit...