AIMC Topic: Aged

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Fully Automated Online Adaptive Radiation Therapy Decision-Making for Cervical Cancer Using Artificial Intelligence.

International journal of radiation oncology, biology, physics
BACKGROUND: Interfraction variations during radiation therapy pose a challenge for patients with cervical cancer, highlighting the benefits of online adaptive radiation therapy (oART). However, adaptation decisions rely on subjective image reviews by...

Transcriptomic analyses of human brains with Alzheimer's disease identified dysregulated epilepsy-causing genes.

Epilepsy & behavior : E&B
BACKGROUND & OBJECTIVE: Alzheimer's Disease (AD) patients at multiple stages of disease progression have a high prevalence of seizures. However, whether AD and epilepsy share pathophysiological changes remains poorly defined. In this study, we levera...

Performance and hypothetical clinical impact of an mNGS-based machine learning model for antimicrobial susceptibility prediction of five ESKAPEE bacteria.

Microbiology spectrum
UNLABELLED: Antimicrobial resistance is an escalating global health crisis, underscoring the urgent need for timely and targeted therapies to ensure effective clinical treatment. We developed a machine learning model based on metagenomic next-generat...

Assessing the association of multi-environmental chemical exposures on metabolic syndrome: A machine learning approach.

Environment international
Metabolic syndrome (MetS) is a major global public health concern due to its rising prevalence and association with increased risks of cardiovascular disease and type 2 diabetes. Emerging evidence suggests that environmental chemical exposures may pl...

Classification of Grades of Subchondral Sclerosis from Knee Radiographic Images Using Artificial Intelligence.

Sensors (Basel, Switzerland)
Osteoarthritis (OA) is the most common joint disease, affecting over 300 million people worldwide. Subchondral sclerosis is a key indicator of OA. Currently, the diagnosis of subchondral sclerosis is primarily based on radiographic images; however, r...

Deep Learning-Driven Abbreviated Shoulder MRI Protocols: Diagnostic Accuracy in Clinical Practice.

Tomography (Ann Arbor, Mich.)
BACKGROUND: Deep learning (DL) reconstruction techniques have shown promise in reducing MRI acquisition times while maintaining image quality. However, the impact of different acceleration factors on diagnostic accuracy in shoulder MRI remains unexpl...

Predicting depression and unravelling its heterogeneous influences in middle-aged and older people populations: a machine learning approach.

BMC psychology
BACKGROUND: Aging has become a global trend, and depression, as an accompanying issue, poses a significant threat to the health of middle-aged and older adults. Existing studies primarily rely on statistical methods such as logistic regression for sm...

Automated machine learning for early prediction of systemic inflammatory response syndrome in acute pancreatitis.

BMC medical informatics and decision making
BACKGROUND: Systemic inflammatory response syndrome (SIRS) is a frequent and serious complication of acute pancreatitis (AP), often associated with increased mortality. This study aims to leverage automated machine learning (AutoML) algorithms to cre...

Predicting coronary heart disease with advanced machine learning classifiers for improved cardiovascular risk assessment.

Scientific reports
Worldwide, coronary heart disease (CHD) is a leading cause of mortality, and its early prediction remains a critical challenge in clinical data analysis. Machine learning (ML) offers valuable diagnostic support by leveraging healthcare data to enhanc...

Automated opportunistic screening for osteoporosis using deep learning-based automatic segmentation and radiomics on proximal femur images from low-dose abdominal CT.

BMC musculoskeletal disorders
RATIONALE AND OBJECTIVES: To establish an automated osteoporosis detection model based on low-dose abdominal CT (LDCT). This model combined a deep learning-based automatic segmentation of the proximal femur with a radiomics-based bone status classifi...