AIMC Topic: Aged

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A noninvasive and highly efficient epigenetic predictive model for efficacy of the GOLP regimen in patients with intrahepatic cholangiocarcinoma.

Cancer letters
The GOLP regimen (Gemcitabine, Oxaliplatin, Lenvatinib and anti-PD1 antibody) has been a promising first-line treatment for advanced intrahepatic cholangiocarcinoma (iCCA). A noninvasive tool to predict the response to GOLP regimen is needed for clin...

Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome.

BMC microbiology
Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data f...

Machine learning models predict risk of lower extremity deep vein thrombosis in hospitalized patients with spontaneous intracerebral hemorrhage.

Scientific reports
Lower extremity deep vein thrombosis is one of the important complications of spontaneous intracerebral hemorrhage. We aimed to develop a risk assessment model to predict the risk of lower extremity DVT during hospitalization in patients with spontan...

Inflammatory, fibrotic and endothelial biomarker profiles in COVID-19 patients during and following hospitalization.

Scientific reports
Survivors of severe COVID-19 often suffer from long-term respiratory issues, but the molecular drivers of this damage remain unclear. This study explored the dynamics of inflammatory, fibrotic, and endothelial biomarkers in hospitalized COVID-19 pati...

Conversational Systems for Social Care in Older Adults: Protocol for a Scoping Review.

JMIR research protocols
BACKGROUND: Social care systems worldwide face increasing demographic and financial pressures. This necessitates exploring innovative technological solutions to enhance service delivery without substantially increasing costs. Conversational interface...

AI Predictive Model of Mortality and Intensive Care Unit Admission in the COVID-19 Pandemic: Retrospective Population Cohort Study of 12,000 Patients.

Journal of medical Internet research
BACKGROUND: One of the main challenges with COVID-19 has been that although there are known factors associated with a worse prognosis, clinicians have been unable to predict which patients, with similar risk factors, will die or require intensive car...

Multi-class subarachnoid hemorrhage severity prediction: addressing challenges in predicting rare outcomes.

Neurosurgical review
Accurately predicting the severity of subarachnoid hemorrhage (SAH) is critical for informing clinical decisions and improving patient outcomes. This study addresses the challenges of imbalanced data in SAH severity classification by employing the Mo...