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Predictive modeling and machine learning show poor performance of clinical, morphological, and hemodynamic parameters for small intracranial aneurysm rupture.

Scientific reports
Small intracranial aneurysms (SIAs) (< 5 mm) are increasingly detected due to advanced imaging, but predicting rupture risk remains challenging. Rupture, though rare, can cause devastating subarachnoid hemorrhage. This study analyzed 141 SIAs (101 un...

Early warning and stratification of the elderly cardiopulmonary dysfunction-related diseases: multicentre prospective study protocol.

BMJ open
INTRODUCTION: In China, there is a lack of standardised clinical imaging databases for multidimensional evaluation of cardiopulmonary diseases. To address this gap, this study protocol launched a project to build a clinical imaging technology integra...

Development of an interpretable machine learning model for frailty risk prediction in older adult care institutions: a mixed-methods, cross-sectional study in China.

BMJ open
OBJECTIVE: To develop and validate an interpretable machine learning (ML)-based frailty risk prediction model that combines real-time health data with validated scale assessments for enhanced decision-making and targeted health management in integrat...

Leveraging heterogeneous tabular of EHRs with prompt learning for clinical prediction.

Journal of biomedical informatics
Electronic Health Records (EHRs) depict patient-related information and have significantly contributed to advancements in healthcare fields. The abundance of EHR data provides exceptional opportunities for developing clinical predictive models. Howev...

Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer's disease in cerebrospinal fluid.

Alzheimer's research & therapy
BACKGROUND: The complex pathogenesis of Alzheimer's disease (AD) has resulted in limited current biomarkers for its classification and diagnosis, necessitating further investigation into reliable universal biomarkers or combinations.

Machine learning-based predictive tools and nomogram for in-hospital mortality in critically ill cancer patients: development and external validation using retrospective cohorts.

BMC medical informatics and decision making
BACKGROUND: The incidence of intensive care unit (ICU) admissions and the corresponding mortality rates among cancer patients are both high. However, the existing scoring systems all lack specificity. This research seeks to establish and validate a p...

Predicting ESWL success for ureteral stones: a radiomics-based machine learning approach.

BMC medical imaging
OBJECTIVES: This study aimed to develop and validate a machine learning (ML) model that integrates radiomics and conventional radiological features to predict the success of single-session extracorporeal shock wave lithotripsy (ESWL) for ureteral sto...

Deep learning-based classification of parotid gland tumors: integrating dynamic contrast-enhanced MRI for enhanced diagnostic accuracy.

BMC medical imaging
BACKGROUND: To evaluate the performance of deep learning models in classifying parotid gland tumors using T2-weighted, diffusion-weighted, and contrast-enhanced T1-weighted MR images, along with DCE data derived from time-intensity curves.

Machine learning-based prognostic prediction for acute ischemic stroke using whole-brain and infarct multi-PLD ASL radiomics.

BMC medical imaging
INTRODUCTION: Accurate early prognostic prediction for acute ischemic stroke (AIS) is essential for guiding personalized treatment. This study aimed to assess the predictive value of radiomics features from whole-brain and infarct cerebral blood flow...

Intralesional and perilesional radiomics strategy based on different machine learning for the prediction of international society of urological pathology grade group in prostate cancer.

BMC medical imaging
OBJECTIVE: To develop and evaluate a intralesional and perilesional radiomics strategy based on different machine learning model to differentiate International Society of Urological Pathology (ISUP) grade > 2 group and ISUP ≤ 2 prostate cancers (PCa)...