AIMC Topic: Aged

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A Machine Learning Approach to Identify a Circulating MicroRNA Signature for Alzheimer Disease.

The journal of applied laboratory medicine
BACKGROUND: Accurate diagnosis of Alzheimer disease (AD) involving less invasive molecular procedures and at reasonable cost is an unmet medical need. We identified a serum miRNA signature for AD that is less invasive than a measure in cerebrospinal ...

Keratinocytic Skin Cancer Detection on the Face Using Region-Based Convolutional Neural Network.

JAMA dermatology
IMPORTANCE: Detection of cutaneous cancer on the face using deep-learning algorithms has been challenging because various anatomic structures create curves and shades that confuse the algorithm and can potentially lead to false-positive results.

Technology-Based Objective Measures Detect Subclinical Axial Signs in Untreated, de novo Parkinson's Disease.

Journal of Parkinson's disease
BACKGROUND: Technology-based objective measures (TOMs) recently gained relevance to support clinicians in the assessment of motor function in Parkinson's disease (PD), although limited data are available in the early phases.

Machine learning versus traditional risk stratification methods in acute coronary syndrome: a pooled randomized clinical trial analysis.

Journal of thrombosis and thrombolysis
Traditional statistical models allow population based inferences and comparisons. Machine learning (ML) explores datasets to develop algorithms that do not assume linear relationships between variables and outcomes and that may account for higher ord...

Machine-learning-based knowledge discovery in rheumatoid arthritis-related registry data to identify predictors of persistent pain.

Pain
Early detection of patients with chronic diseases at risk of developing persistent pain is clinically desirable for timely initiation of multimodal therapies. Quality follow-up registries may provide the necessary clinical data; however, their design...

Quantifying the Association Between Psychotherapy Content and Clinical Outcomes Using Deep Learning.

JAMA psychiatry
IMPORTANCE: Compared with the treatment of physical conditions, the quality of care of mental health disorders remains poor and the rate of improvement in treatment is slow, a primary reason being the lack of objective and systematic methods for meas...

Development of a periodontitis risk assessment model for primary care providers in an interdisciplinary setting.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: Periodontitis (PD), a form of gum disease, is a major public health concern as it is globally prevalent and harms both individual quality of life and economic productivity. Global cost in lost productivity is estimated at US$54 billion an...