AIMC Topic: Aged

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Association of acute kidney injury with 1-year mortality in granulomatosis with polyangiitis patients: a cohort study using mediation analyses and machine learning.

Rheumatology international
To investigate the correlation between acute kidney injury (AKI) and 1-year mortality in patients with granulomatosis with polyangiitis (GPA). Clinical data for GPA patients were extracted from the MIMIC-IV (version 3.0) database. Logistic and Cox re...

Machine learning technique-based four-autoantibody test for early detection of esophageal squamous cell carcinoma: a multicenter, retrospective study with a nested case-control study.

BMC medicine
BACKGROUND: Autoantibodies represent promising diagnostic blood-based biomarkers that may be generated prior to the first clinically detectable signs of cancers. In present study, we aimed to identify a novel optimized autoantibody panel with high di...

Constructing a neural network model based on tumor-infiltrating lymphocytes (TILs) to predict the survival of hepatocellular carcinoma patients.

PeerJ
BACKGROUND: Hepatocellular carcinoma (HCC) is the most common primary liver cancer worldwide, and early pathological diagnosis is crucial for formulating treatment plans. Despite the widespread attention to pathology in the treatment of HCC patients,...

Automatic determination of the resection plane for shoulder arthroplasty in arthritic humeri: a deep learning model.

Journal of shoulder and elbow surgery
BACKGROUND: The humeral head resection plane relies on the anatomic neck as a reference for shoulder arthroplasty planning and accurate intraoperative placement of the humeral component. However, osteophytes and deformity associated with osteoarthrit...

Prostate Cancer Risk Stratification and Scan Tailoring Using Deep Learning on Abbreviated Prostate MRI.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: MRI plays a critical role in prostate cancer (PCa) detection and management. Bi-parametric MRI (bpMRI) offers a faster, contrast-free alternative to multi-parametric MRI (mpMRI). Routine use of mpMRI for all patients may not be necessary,...

The establishment of machine learning prognostic prediction models for pineal region tumors based on SEER-A multicenter real-world study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND: Pineal region tumors (PRT) are rare intracranial neoplasms with diverse pathological types and growth characteristics, leading to varied clinical manifestations. This study aims to develop machine learning (ML) models for survival predict...

Improved radiological diagnosis of osteoporotic vertebral fragility fractures following UK-wide interventions and re-audit-can this be maintained and translated into clinical practice?

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
UNLABELLED: To determine the potential economic, morbidity and mortality impact of improvements in reporting of vertebral fragility fractures (VFFs) following a complete audit cycle. Six percent interval increase in reporting of moderate/severe VFFs ...

Cerebrospinal fluid inflammatory cytokines as prognostic indicators for cognitive decline across Alzheimer's disease spectrum.

Journal of Alzheimer's disease : JAD
BackgroundNeuroinflammation actively contributes to the pathophysiology of Alzheimer's disease (AD); however, the value of neuroinflammatory biomarkers for disease-staging or predicting disease progression remains unclear.ObjectiveTo investigate diag...