BACKGROUND: Cardiovascular dysfunction frequently accompanies aging and is often worsened by adverse lifestyle factors and genetic susceptibility. The apolipoprotein E (APOE) gene modulates susceptibility to cardiovascular disease, but how exercise a...
Accurate subcellular segmentation is crucial for understanding cellular processes, but traditional methods struggle with noise and complex structures. Convolutional neural networks improve accuracy but require large, time-consuming, and biased manual...
ACS biomaterials science & engineering
Dec 18, 2025
The skeletal system exhibits remarkable mechanical properties, serving as the primary supportive framework in vertebrates. Dysregulation of bone metabolic activity can alter bone quality and quantity, leading to skeletal deformity, pain, or disease. ...
Omics approaches have emerged as indispensable tools in unravelling the intricate molecular landscape of cardiovascular disease (CVD) by providing comprehensive insights into the underlying mechanisms driving CVD pathogenesis, progression, and respon...
Endocrine-disrupting chemicals (EDCs) are pervasive environmental hazards that have been linked to osteoporosis (OP), though causal mechanisms remain elusive. Employing an integrated multiomics framework, this study combined bidirectional Mendelian r...
This study develops an innovative approach that integrates a colorimetric sensor array (CSA) composed of phenylalanine-modified MnO nanozymes with advanced algorithms, aiming to detect the anthrax biomarker 2,6-pyridine dicarboxylic acid (2,6-PDA) an...
To overcome limitations of flexible thermoacoustic devices in low-frequency emission and sensing, we present a resonance-adjustable graphene sound device (RAGSD) inspired by frog vocal sacs. Integrating laser-induced graphene (LIG) with a deformable ...
Natural selection has produced diverse vision systems, from simple patches of photoreceptors to complex camera eyes, representing just one set of evolutionary outcomes. Computational evolution offers a way to systematically test hypotheses, isolate i...
Cardiovascular disease is the leading global cause of death, underscoring the need for accurate assessment of myocardial injury. The current gold standard, bright-blood late gadolinium enhanced MRI, suffers from poor contrast at the blood-scar interf...
Retinal vein cannulation (RVC) is an emerging method for treating retinal vein occlusion (RVO). The success of this procedure depends on surgeon expertise and, recently, robotic assistance. This paper proposes an autonomous RVC workflow leveraging de...
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