AIMC Topic: Animals
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Strategies to Decipher Neuron Identity from Extracellular Recordings in Behaving Nonhuman Primates.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Aug 6, 2025
Identification of the neuron type is critical when using extracellular recordings in awake, behaving animal subjects to understand computation in neural circuits. Yet, modern recording probes have limited power to resolve neuron identity. Here, we pr...
Advancing fishery dependent and independent habitat assessments using automated image analysis: A fisheries management agency case study.
PloS one
Aug 6, 2025
Advances in artificial intelligence and machine learning have revolutionised data analysis, including in the field of marine and fisheries sciences. However, many fisheries agencies manage sensitive or proprietary data that cannot be shared externall...
Predicting Subcutaneous Antibody Bioavailability Using Ensemble Protein Language Models.
Molecular pharmaceutics
Aug 5, 2025
Monoclonal antibodies are pivotal in modern therapeutics, yet predicting their subcutaneous bioavailability remains challenging due to the intricacies of the SC environment and the limitations of traditional experimental models. In this study, we int...
Precision medicine in substance use disorders: Integrating behavioral, environmental, and biological insights.
Neuroscience and biobehavioral reviews
Aug 5, 2025
Substance use disorders (SUD) are chronic, relapsing conditions marked by high variability in treatment response and frequent relapse. This variability arises from complex interactions among behavioral, environmental, and biological factors unique to...
A computational framework for inferring species dynamics and interactions with applications in microbiota ecology.
NPJ systems biology and applications
Aug 5, 2025
We present MBPert, a generic computational framework for inferring species interactions and predicting dynamics in time-evolving ecosystems from perturbation and time-series data. In this work, we contextualize the framework in microbial ecosystem mo...
Bioinformatics analysis of Rho-signal transduction genes in postmenopausal osteoporosis and periodontitis.
Scientific reports
Aug 5, 2025
Postmenopausal osteoporosis (PMOP) increases the risk of periodontitis (PD), yet the shared mechanisms remain unclear. Rho-signal transduction genes may play a role due to their involvement in bone remodeling. This study aimed to explore Rho-related ...
Seeker-M: A bionic mantis shrimp robot with an adjustable-mass flexible spine.
Bioinspiration & biomimetics
Aug 5, 2025
To enhance the motion flexibility and environmental adaptability of underwater robots, this study proposes a novel design, Seeker-M, inspired by the locomotion mechanism of the mantis shrimp. The robot imitates the mantis shrimp's multi-pleopod swimm...
Recent progress in multifunctional theranostic hydrogels: the cornerstone of next-generation wound care technologies.
Biomaterials science
Aug 5, 2025
Theranostic hydrogels represent a groundbreaking approach by integrating therapeutic and diagnostic capabilities within a single platform, enabling real-time monitoring of wounds and precise treatment applications. These advanced materials are engine...
Subsecond Analysis of Locomotor Activity in Parkinsonian Mice.
eNeuro
Aug 5, 2025
The degeneration of midbrain dopamine (DA) neurons disrupts the neural control of natural behavior, such as walking, posture, and gait in Parkinson's disease. While some aspects of motor symptoms can be managed by DA replacement therapies, others res...
Integrative transcriptomic analysis reveals oligodendrocyte lineage switching in multiple sclerosis.
Life science alliance
Aug 4, 2025
Multiple sclerosis (MS) is a chronic disease of the central nervous system. The occurrence of MS is a phased process while its cause is still unclear. Here, by combining white matter single-nucleus transcriptomic datasets from MS and control samples,...
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