FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Sep 15, 2025
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent hepatic metabolic disorder with a rising global incidence. Epigenetic modifications-such as methylation, acetylation, phosphorylation, and ubiquitination-play critical ro...
Mitochondrial function plays a crucial role in understanding the pathogenesis of acute myocardial infarction.This study investigates mitochondrial function-related genes (MFRGs) in acute myocardial infarction (AMI) through bioinformatics and rigorous...
AIMS: This study investigates the role of macrophage histone lactylation-a protein modification-in atherosclerosis progression, particularly in peripheral artery disease (PAD), and evaluates the therapeutic potential of the herbal formula Ruan Jian Q...
Retained placenta (RP) is a reproductive disorder that causes significant financial losses to the dairy industry. Predicting RP risk in cows post-calving is a challenging task. This study aimed to evaluate the predictive capabilities of five machine ...
BACKGROUNDS: The etiology of depression involves chronic stress, a recognized determinant of onset and severity. This study adopts a translational approach, utilizing a mouse model and a clinical cohort to explore the relationship between chronic str...
Smartphone-integrated nanozyme technologies (S-INTs) have emerged as a promising solution for rapid, on-site food safety analysis, addressing the detection of foodborne pathogens, contaminants, and hazards. While the applications of nanozymes in food...
Systemic lupus erythematosus (SLE), a multifaceted autoimmune disorder, has lupus nephritis (LN) as one of its grave complications and is strongly associated with dyslipidemia. This investigation sought to delineate renal-specific lipid metabolism-re...
The digitization of natural history specimens has unlocked opportunities for large-scale phenotypic trait analysis. In recent years, deep learning has shown significant results in accurately predicting annotations on 2D specimen photographs. However,...
Antibiotic-resistant (AR) bacterial wound infections (WIs) impose major burdens on healthcare systems, exacerbated by ineffective therapies and stalled antibiotic development. Phage therapy and phage-derived enzymes have gained traction as potent alt...
Nearly all methods of mass-spectrometry-based proteomics rely on knowing the proteome of the species. In less studied organisms without annotated genomes, it can seem impossible to perform proteomic analysis. In this study, we sought to answer the qu...
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