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A Computer-Aided Diagnosis System Using Artificial Intelligence for the Diagnosis and Characterization of Thyroid Nodules on Ultrasound: Initial Clinical Assessment.

Thyroid : official journal of the American Thyroid Association Feb 28, 2017
BACKGROUND: An initial clinical assessment is described of a new, commercially available, computer-aided diagnosis (CAD) system using artificial intelligence (AI) for thyroid ultrasound, and its performance is evaluated in the diagnosis of malignant ...
Adult Sensitivity and Specificity Male Middle Aged Diagnosis, Computer-Assisted Humans Artificial Intelligence Area Under Curve Female Aged Biopsy, Fine-Needle Carcinoma, Papillary Biopsy, Large-Core Needle Thyroid Cancer, Papillary Thyroid Diseases Thyroid Neoplasms Ultrasonography Thyroid Nodule ROC Curve
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A novel hierarchical selective ensemble classifier with bioinformatics application.

Artificial intelligence in medicine Feb 27, 2017
Selective ensemble learning is a technique that selects a subset of diverse and accurate basic models in order to generate stronger generalization ability. In this paper, we proposed a novel learning algorithm that is based on parallel optimization a...
Reproducibility of Results ROC Curve Protein Interaction Maps Computational Biology Databases, Genetic Proteins Area Under Curve Data Mining RNA, Transfer Machine Learning
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Prospective identification of hematopoietic lineage choice by deep learning.

Nature methods Feb 20, 2017
Differentiation alters molecular properties of stem and progenitor cells, leading to changes in their shape and movement characteristics. We present a deep neural network that prospectively predicts lineage choice in differentiating primary hematopoi...
Male Image Processing, Computer-Assisted Area Under Curve Cell Differentiation Trans-Activators Neural Networks, Computer Machine Learning Biomarkers Animals Mice, Mutant Strains Time-Lapse Imaging Cell Lineage Proto-Oncogene Proteins Hematopoietic Stem Cells Gene Knock-In Techniques
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Predicting antimicrobial peptides with improved accuracy by incorporating the compositional, physico-chemical and structural features into Chou's general PseAAC.

Scientific reports Feb 13, 2017
Antimicrobial peptides (AMPs) are important components of the innate immune system that have been found to be effective against disease causing pathogens. Identification of AMPs through wet-lab experiment is expensive. Therefore, development of effic...
ROC Curve Antiviral Agents Support Vector Machine Databases, Protein Chemical Phenomena Antimicrobial Cationic Peptides Area Under Curve Antifungal Agents
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Integrated Machine Learning Approaches for Predicting Ischemic Stroke and Thromboembolism in Atrial Fibrillation.

AMIA ... Annual Symposium proceedings. AMIA Symposium Feb 10, 2017
Atrial fibrillation (AF) is a common cardiac rhythm disorder, which increases the risk of ischemic stroke and other thromboembolism (TE). Accurate prediction of TE is highly valuable for early intervention to AF patients. However, the prediction perf...
Stroke Models, Biological Female Thromboembolism Atrial Fibrillation Risk Factors Brain Ischemia Male Humans Area Under Curve Machine Learning Registries Computer Simulation Prognosis
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Structured Pyramidal Neural Networks.

International journal of neural systems Feb 9, 2017
The Pyramidal Neural Networks (PNN) are an example of a successful recently proposed model inspired by the human visual system and deep learning theory. PNNs are applied to computer vision and based on the concept of receptive fields. This paper prop...
Neural Networks, Computer Female Male Time Factors Humans Pattern Recognition, Automated ROC Curve Blood Cells Image Processing, Computer-Assisted Pyramidal Cells Support Vector Machine Visual Pathways Models, Neurological Area Under Curve
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Classification of nervous system withdrawn and approved drugs with ToxPrint features via machine learning strategies.

Computer methods and programs in biomedicine Feb 9, 2017
BACKGROUND AND OBJECTIVES: Early-phase virtual screening of candidate drug molecules plays a key role in pharmaceutical industry from data mining and machine learning to prevent adverse effects of the drugs. Computational classification methods can d...
Product Surveillance, Postmarketing Nervous System Benzene Ethylamines Pattern Recognition, Automated Support Vector Machine Safety-Based Drug Withdrawals Humans Drug Monitoring False Positive Reactions Carbon Algorithms Pharmaceutical Preparations Area Under Curve Drug Approval Data Mining Patient Safety Risk Toluene Computer Simulation Sensitivity and Specificity Linear Models
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Enhancing the Biological Relevance of Machine Learning Classifiers for Reverse Vaccinology.

International journal of molecular sciences Feb 1, 2017
Reverse vaccinology (RV) is a bioinformatics approach that can predict antigens with protective potential from the protein coding genomes of bacterial pathogens for subunit vaccine design. RV has become firmly established following the development of...
Support Vector Machine Area Under Curve Humans Bacterial Proteins Mutagenesis Machine Learning Epitopes Antigens, Bacterial ROC Curve Bacterial Vaccines Computational Biology Epitope Mapping Vaccines, Subunit
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Predicting prostate tumour location from multiparametric MRI using Gaussian kernel support vector machines: a preliminary study.

Australasian physical & engineering sciences in medicine Jan 24, 2017
The performance of a support vector machine (SVM) algorithm was investigated to predict prostate tumour location using multi-parametric MRI (mpMRI) data. The purpose was to obtain information of prostate tumour location for the implementation of bio-...
Support Vector Machine Magnetic Resonance Imaging Area Under Curve Prostatic Neoplasms Aged Male Middle Aged ROC Curve Humans
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Neural network prediction of severe lower intestinal bleeding and the need for surgical intervention.

The Journal of surgical research Dec 30, 2016
BACKGROUND: The prognosis for patients with severe acute lower intestinal bleeding (ALIB) may be assessed by complex artificial neural networks (ANNs) or user-friendly regression-based models. Comparisons between these modalities are limited, and pre...
Aged, 80 and over Young Adult Adult Male Middle Aged Retrospective Studies Rectal Diseases Risk Assessment Female Area Under Curve Humans Severity of Illness Index Risk Factors Gastrointestinal Hemorrhage Neural Networks, Computer Adolescent Aged Colonic Diseases Decision Support Techniques ROC Curve Prognosis
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