AIMC Topic: Asian People
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Rate of brain aging associates with future executive function in Asian children and older adults.
eLife
Jun 16, 2025
Brain age has emerged as a powerful tool to understand neuroanatomical aging and its link to health outcomes like cognition. However, there remains a lack of studies investigating the rate of brain aging and its relationship to cognition. Furthermore...
Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations.
Current osteoporosis reports
May 24, 2025
PURPOSE OF REVIEW: Genome-wide association studies (GWAS) have significantly advanced osteoporosis research by identifying genetic loci associated with bone mineral density (BMD) and fracture risk. However, disparities persist due to the underreprese...
African People
Low Density Lipoprotein Receptor-Related Protein-5
Humans
Machine Learning
Core Binding Factor Alpha 1 Subunit
Bone Density
Asian People
Osteoporosis
White People
Genome-Wide Association Study
Gene-Environment Interaction
Genomics
Osteoporotic Fractures
Genetic Predisposition to Disease
Preterm birth trends and risk factors in a multi-ethnic Asian population: A retrospective study from 2017 to 2023, can we screen and predict this?
Annals of the Academy of Medicine, Singapore
May 21, 2025
INTRODUCTION: Preterm birth (PTB) remains a leading cause of perinatal morbidity and mortality worldwide. Understanding Singapore's PTB trends and associated risk factors can inform effective strategies for screening and intervention. This study anal...
Circulating fibroblast growth factor 21 is associated with blood pressure in the Chinese population: a community-based study.
Annals of medicine
May 12, 2025
BACKGROUND: Our research team previously found that fibroblast growth factor (FGF) 21, a circulating hormone, was significantly associated with atherosclerosis in human and animal models. The relationship between FGF21 and blood pressure (BP) is rare...
Predicting isolated impaired glucose tolerance without oral glucose tolerance test using machine learning in Chinese Han men.
Frontiers in endocrinology
Apr 24, 2025
BACKGROUND: Isolated Impaired Glucose Tolerance (I-IGT) represents a specific prediabetic state that typically requires a standardized oral glucose tolerance test (OGTT) for diagnosis. This study aims to predict glucose tolerance status in Chinese Ha...
Deep learning-based normative database of anterior chamber dimensions for angle closure assessment: the Singapore Chinese Eye Study.
The British journal of ophthalmology
Mar 20, 2025
BACKGROUND/ AIMS: The lack of context for anterior segment optical coherence tomography (ASOCT) measurements impedes its clinical utility. We established the normative distribution of anterior chamber depth (ACD), area (ACA) and width (ACW) and lens ...
Prediction of insulin resistance using multiple adaptive regression spline in Chinese women.
Endocrine journal
Feb 1, 2025
Insulin resistance (IR) is the core for type 2 diabetes and metabolic syndrome. The homeostasis assessment model is a straightforward and practical tool for quantifying insulin resistance (HOMA-IR). Multiple adaptive regression spline (MARS) is a mac...
Prediction Trough Concentrations of Valproic Acid Among Chinese Adult Patients with Epilepsy Using Machine Learning Techniques.
Pharmaceutical research
Jan 22, 2025
OBJECTIVE: This study aimed to establish an optimal model based on machine learning (ML) to predict Valproic acid (VPA) trough concentrations in Chinese adult epilepsy patients.
A machine learning approach for estimating Eastern Asian origins from massive screening of Y chromosomal short tandem repeats polymorphisms.
International journal of legal medicine
Jan 8, 2025
Inferring the ancestral origin of DNA evidence recovered from crime scenes is crucial in forensic investigations, especially in the absence of a direct suspect match. Ancestry informative markers (AIMs) have been widely researched and commercially de...
Predicting structure-targeted food bioactive compounds for middle-aged and elderly Asians with myocardial infarction: insights from genetic variations and bioinformatics-integrated deep learning analysis.
Food & function
Sep 16, 2024
Myocardial infarction (MI) is a significant global health issue. Despite the advances in genome-wide association studies, a complete genetic and molecular understanding of MI is elusive and needs to be fully explored. This study aimed to elucidate th...
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