AIMC Topic: Benzhydryl Compounds

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Quantitative analysis of bisphenol analogue mixtures by terahertz spectroscopy using machine learning method.

Food chemistry Feb 19, 2021
Quantitative analysis of complex mixtures is a great challenge for spectral analysis. Bisphenol A (BpA) is a chemical predominantly used in manufacturing and is being replaced by other analogs due to its potential toxicity. Reliability methods is hen...
Reproducibility of Results Phenols Benzhydryl Compounds Terahertz Spectroscopy Machine Learning
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BPA, BADGE and analogues: A new multi-analyte LC-ESI-MS/MS method for their determination and their in vitro (anti)estrogenic and (anti)androgenic properties.

Chemosphere Dec 28, 2018
Information on the occurrence and endocrine potencies of analogues of bisphenol A (BPA) and diglycidyl ester derivatives (BDGEs) of BPA and BPF is limited. Such information is, however, important as the current debate on BPA and the lowered BPA migra...
Tandem Mass Spectrometry Esters Benzhydryl Compounds Estrogen Antagonists Europe Chromatography, Liquid Phenols Androgen Antagonists Food Contamination
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Aminolated and Thiolated PEG-Covered Gold Nanoparticles with High Stability and Antiaggregation for Lateral Flow Detection of Bisphenol A.

Small (Weinheim an der Bergstrasse, Germany) Dec 27, 2017
The few lateral flow assays (LFAs) established for detecting the endocrine disrupting chemical bisphenol A (BPA) have employed citrate-stabilized gold nanoparticles (GNPs), which have inevitable limitations and instability issues. To address these li...
Metal Nanoparticles Polyethylene Glycols Benzhydryl Compounds Biosensing Techniques Phenols Gold
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Distribution, variability, and predictors of urinary bisphenol A levels in 50 North Carolina adults over a six-week monitoring period.

Environment international Dec 18, 2017
Bisphenol A (BPA) is commonly manufactured to make polycarbonate plastics and epoxy resins for use in consumer products and packaged goods. BPA has been found in several different types of environmental media (e.g., food, dust, and air). Many cross-s...
Humans Biomarkers Environmental Monitoring Phenols Benzhydryl Compounds North Carolina
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Physiological based pharmacokinetic modeling to estimate in vivo Ki of ketoconazole on renal P-gp using human drug-drug interaction study result of fesoterodine and ketoconazole.

Drug metabolism and pharmacokinetics Nov 15, 2017
This study was conducted to estimate in vivo inhibition constant (Ki) of ketoconazole on renal P-glycoprotein (P-gp) using human drug-drug interaction (DDI) study result of fesoterodine and ketoconazole. Fesoterodine is a prodrug which is extensively...
Humans Male Kidney Muscarinic Antagonists Cytochrome P-450 CYP3A Inhibitors Drug Interactions Liver Models, Biological ATP Binding Cassette Transporter, Subfamily B, Member 1 Cross-Over Studies Benzhydryl Compounds Ketoconazole
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Bioequivalence of fixed-dose combinations of dapagliflozin and metformin with single-component tablets in healthy subjects and the effect of food on bioavailability.

Clinical pharmacology in drug development Oct 20, 2015
The pharmacokinetics (PK) of dapagliflozin and metformin administered as fixed-dose combination (FDC) tablets (2.5 mg dapagliflozin/850 mg metformin or 5 mg dapagliflozin/1000 mg metformin) or as separate tablets in healthy subjects were evaluated in...
Humans Female Young Adult Therapeutic Equivalency Food-Drug Interactions Area Under Curve Glucosides Tablets Adolescent Biological Availability Adult Fasting Cross-Over Studies Male Hypoglycemic Agents Middle Aged Benzhydryl Compounds Drug Combinations Metformin
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Effects of xenoestrogens in human M1 and M2 macrophage migration, cytokine release, and estrogen-related signaling pathways.

Environmental toxicology May 26, 2015
Bisphenol A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and di(n-butyl)phthalate (DBP) are environmental estrogens that have been associated with a wide range of adverse health outcomes for which inflammation has also been hypothesized as a potentially ...
Lipopolysaccharides Phenols Interleukin-1beta NF-kappa B Inflammation Signal Transduction Cell Movement Diethylhexyl Phthalate Benzhydryl Compounds Cell Migration Assays, Macrophage Chemotaxis, Leukocyte Tumor Necrosis Factor-alpha Cells, Cultured Macrophages Cytokines Female Middle Aged Estradiol Humans
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Exploring the toxicological impact of bisphenol a exposure on psoriasis through network toxicology, machine learning, and multi-dimensional bioinformatics analysis.

Journal of environmental management Jun 1, 2025
Psoriasis is a common immune - mediated skin disease, the pathogenesis of which is not completely elucidated. Environmental factors are key to its onset and progression. Bisphenol A (BPA) is a ubiquitous environmental pollutant that endangers human h...
Machine Learning Computational Biology Psoriasis Phenols Humans Environmental Pollutants Benzhydryl Compounds Bisphenol A Compounds
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[Determination of four bisphenol environmental hormone residues in infant serum by liquid chromatography-tandem mass spectrometry].

Se pu = Chinese journal of chromatography Dec 8, 2020
Bisphenols are important industrial raw materials that are widely used to produce plastic bottles (feeding bottles), infant cups, and food and beverage (milk powder) cans. Because of the estrogen-like effect of bisphenols, even low-dose intake of the...
Benzhydryl Compounds Infant Phenols Chromatography, High Pressure Liquid Humans Tandem Mass Spectrometry Female Male
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Sodium glucose co-transporter 2 inhibitors and cardiovascular event protections: how applicable are clinical trials and observational studies to real-world patients?

BMJ open diabetes research & care Dec 1, 2019
OBJECTIVE: This study evaluated the characteristics of new users of sodium glucose co-transporter 2 inhibitors (SGLT2i) in clinical practice to assess the applicability of the findings from clinical trials (Empagliflozin, Cardiovascular Outcomes and ...
Diabetic Angiopathies Sodium-Glucose Transporter 2 Inhibitors Blood Glucose Cohort Studies Glycated Hemoglobin Diabetes Mellitus, Type 2 Male Humans Practice Patterns, Physicians' Glucosides Observational Studies as Topic Bridged Bicyclo Compounds, Heterocyclic Retrospective Studies Female Cardiovascular Diseases Benzhydryl Compounds Canagliflozin Aged Middle Aged Clinical Trials as Topic Aged, 80 and over Adult
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