AI Medical Compendium Topic:
Biomarkers, Tumor

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Prediction of survival outcomes in patients with epithelial ovarian cancer using machine learning methods.

Journal of gynecologic oncology
OBJECTIVES: The aim of this study was to develop a new prognostic classification for epithelial ovarian cancer (EOC) patients using gradient boosting (GB) and to compare the accuracy of the prognostic model with the conventional statistical method.

Deep learning can see the unseeable: predicting molecular markers from MRI of brain gliomas.

Clinical radiology
This paper describes state-of-the-art methods for molecular biomarker prediction utilising magnetic resonance imaging. This review paper covers both classical machine learning approaches and deep learning approaches to identifying the predictive feat...

Predicting breast tumor proliferation from whole-slide images: The TUPAC16 challenge.

Medical image analysis
Tumor proliferation is an important biomarker indicative of the prognosis of breast cancer patients. Assessment of tumor proliferation in a clinical setting is a highly subjective and labor-intensive task. Previous efforts to automate tumor prolifera...

Machine learning analysis of gene expression data reveals novel diagnostic and prognostic biomarkers and identifies therapeutic targets for soft tissue sarcomas.

PLoS computational biology
Based on morphology it is often challenging to distinguish between the many different soft tissue sarcoma subtypes. Moreover, outcome of disease is highly variable even between patients with the same disease. Machine learning on transcriptome sequenc...

Pancreatic cancer biomarker detection by two support vector strategies for recursive feature elimination.

Biomarkers in medicine
AIM: Pancreatic cancer is one of the worst malignant tumors in prognosis. Therefore, to reduce the mortality rate of pancreatic cancer, early diagnosis and prompt treatment are particularly important.

High-Quality Immunohistochemical Stains Through Computational Assay Parameter Optimization.

IEEE transactions on bio-medical engineering
Accurate profiling of tumors using immunohistochemistry (IHC) is essential in cancer diagnosis. The inferences drawn from IHC-stained images depend to a great extent on the quality of immunostaining, which is in turn affected strongly by assay parame...

Novel Regularization Method for Biomarker Selection and Cancer Classification.

IEEE/ACM transactions on computational biology and bioinformatics
Variable selection has attracted more attention in big data and machine learning fields. In high dimensional data analysis, many relevant variables or variable groups are widely found. For example, people pay more interests to biological pathway or r...

Emerging Applications of Artificial Intelligence in Neuro-Oncology.

Radiology
Due to the exponential growth of computational algorithms, artificial intelligence (AI) methods are poised to improve the precision of diagnostic and therapeutic methods in medicine. The field of radiomics in neuro-oncology has been and will likely c...

Rapid LC-MS/MS quantification of cancer related acetylated polyamines in human biofluids.

Talanta
Increased urinary acetylated polyamines (APs) are reported as cancer biomarkers in many studies. N,N-diacetylspermine has been proposed as a biomarker indicative of different cancers in urine and plasma. N-Acetylspermine has previously been found to ...