The Nancy histological index (NHI) is a measure of disease activity within colorectal biopsies and a predictor of clinical outcome in ulcerative colitis (UC). We measured interobserver agreement (IOA) during NHI scoring of 20 colorectal biopsies in U...
OBJECTIVES: Renal biopsy is the gold standard for the diagnosis of glomerular diseases including membranous nephropathy (MN), however, it faces challenges in accuracy, objectivity, and reproducibility of tissue evaluation. This study aims to develop ...
INTRODUCTION: Histopathological evaluation of prostate biopsies using the Gleason scoring system is critical for prostate cancer diagnosis and treatment selection. However, grading variability among pathologists can lead to inconsistent assessments, ...
BACKGROUND: Multiparametric magnetic resonance imaging (mpMRI) has significantly advanced prostate cancer (PCa) detection, yet decisions on invasive biopsy with moderate prostate imaging reporting and data system (PI-RADS) scores remain ambiguous.
Approximately 40% of patients with rheumatoid arthritis do not respond to individual biologic therapies, while biomarkers predictive of treatment response are lacking. Here we analyse RNA-sequencing (RNA-Seq) of pre-treatment synovial tissue from the...
Helicobacter pylori (HP) have chronically infected more than half of the world's population and is a cause of chronic gastritis, peptic ulcers and gastric carcinoma. The manual detection of HP in a glass slide with a microscope is extremely time-cons...
BACKGROUND: Indeterminate pulmonary nodules (IPNs) are commonly biopsied to ascertain a diagnosis of lung cancer, but many are ultimately benign. The Lung Cancer Prediction (LCP) score is a commercially available deep learning radiomic model with str...
BACKGROUND: Transrectal (TR) and transperineal (TP) biopsies are commonly used methods for diagnosing prostate cancer. However, their comparative effectiveness in conjunction with machine learning (ML) techniques remains underexplored. This study aim...
AIM: To develop and validate a combined model based on magnetic resonance imaging (MRI), and whole-slide imaging (WSI) to predict pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in breast cancer.
European journal of obstetrics, gynecology, and reproductive biology
Jun 4, 2025
OBJECTIVE: Hysteroscopy is commonly used for diagnosing benign endometrial conditions, but its diagnostic performance in malignancies post-treatment surveillance has not been evaluated. This study evaluated the correlation between hysteroscopic appea...
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