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Carcinoma, Hepatocellular

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Predicting hepatocellular carcinoma survival with artificial intelligence.

Scientific reports
Despite the extensive research on hepatocellular carcinoma (HCC) exploring various treatment strategies, the survival outcomes have remained unsatisfactory. The aim of this research was to evaluate the ability of machine learning (ML) methods in pred...

An interpretable ensemble model combining handcrafted radiomics and deep learning for predicting the overall survival of hepatocellular carcinoma patients after stereotactic body radiation therapy.

Journal of cancer research and clinical oncology
PURPOSE: Hepatocellular carcinoma (HCC) remains a global health concern, marked by increasing incidence rates and poor outcomes. This study seeks to develop a robust predictive model by integrating radiomics and deep learning features with clinical d...

Deep Learning Radiopathomics Models Based on Contrast-enhanced MRI and Pathologic Imaging for Predicting Vessels Encapsulating Tumor Clusters and Prognosis in Hepatocellular Carcinoma.

Radiology. Imaging cancer
Purpose To develop deep learning (DL) radiopathomics models based on contrast-enhanced MRI and pathologic imaging to predict vessels encapsulating tumor clusters (VETC) and survival in hepatocellular carcinoma (HCC). Materials and Methods In this ret...

Deep learning for hepatocellular carcinoma recurrence before and after liver transplantation: a multicenter cohort study.

Scientific reports
Hepatocellular carcinoma (HCC) recurrence after liver transplantation (LT) is a major contributor to mortality. We developed a recurrence prediction system for HCC patients before and after LT. Data from patients with HCC who underwent LT were retros...

Opportunistic Detection of Hepatocellular Carcinoma Using Noncontrast CT and Deep Learning Artificial Intelligence.

Journal of the American College of Radiology : JACR
OBJECTIVE: Hepatocellular carcinoma (HCC) poses a heavy global disease burden; early diagnosis is critical to improve outcomes. Opportunistic screening-the use of imaging data acquired for other clinical indications for disease detection-as well as t...

Machine learning analysis identified NNMT as a potential therapeutic target for hepatocellular carcinoma based on PCD-related genes.

Scientific reports
Programmed cell death (PCD) plays a critical role in cancer biology, influencing tumor progression and treatment response. This study aims to investigate the role of PCD-related genes in hepatocellular carcinoma (HCC), identifying potential prognosti...

MRI-Based Topology Deep Learning Model for Noninvasive Prediction of Microvascular Invasion and Assisting Prognostic Stratification in HCC.

Liver international : official journal of the International Association for the Study of the Liver
BACKGROUND & AIMS: Microvascular invasion (MVI) is associated with poor prognosis in hepatocellular carcinoma (HCC). Topology may improve the predictive performance and interpretability of deep learning (DL). We aimed to develop and externally valida...