AIMC Topic: Carcinoma, Hepatocellular

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Autophagy-related gene SQSTM1 predicts the prognosis of hepatocellular carcinoma.

Computers in biology and medicine
BACKGROUND: The relationship between autophagy and the progression of hepatocellular carcinoma (HCC) is notably substantial, yet the underlying mechanisms remain incompletely elucidated. Our objective is to construct a predictive model, thereby provi...

Predicting hepatocellular carcinoma response to TACE: A machine learning study based on 2.5D CT imaging and deep features analysis.

European journal of radiology
OBJECTIVES: Prior to the commencement of treatment, it is essential to establish an objective method for accurately predicting the prognosis of patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE). In this st...

Modality-Aware Distillation Network for Microvascular Invasion Prediction of Hepatocellar Carcinoma From MRI Images.

IEEE transactions on bio-medical engineering
Microvascular invasion (MVI) of hepatocellular carcinoma (HCC) is a crucial histopathologic prognostic factor associated with cancer recurrence after liver transplantation or hepatectomy. Recently, clinicoradiologic characteristics are combined with ...

Integration of Bulk RNA and Single-Cell Analyses Reveal Distinct Expression Patterns of Anoikis-Related Genes and the Immunosuppressive Role of NQO1 Macrophages in Hepatocellular Carcinoma.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Anoikis resistance plays a crucial role in the proliferation, metastasis, and invasion of hepatocellular carcinoma (HCC). However, the key genes involved remain to be identified. This study aimed to investigate the prognostic value and impact of anoi...

FasNet: a hybrid deep learning model with attention mechanisms and uncertainty estimation for liver tumor segmentation on LiTS17.

Scientific reports
Liver cancer, especially hepatocellular carcinoma (HCC), remains one of the most fatal cancers globally, emphasizing the critical need for accurate tumor segmentation to enable timely diagnosis and effective treatment planning. Traditional imaging te...

Unsupervised machine learning-based stratification and immune deconvolution of liver hepatocellular carcinoma.

BMC cancer
BACKGROUND: Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer and a leading cause of cancer-related deaths globally. The tumour microenvironment (TME) influences treatment response and prognosis, yet its heterogeneity remains ...

Interactive Explainable Deep Learning Model for Hepatocellular Carcinoma Diagnosis at Gadoxetic Acid-enhanced MRI: A Retrospective, Multicenter, Diagnostic Study.

Radiology. Imaging cancer
Purpose To develop an artificial intelligence (AI) model based on gadoxetic acid-enhanced MRI to assist radiologists in hepatocellular carcinoma (HCC) diagnosis. Materials and Methods This retrospective study included patients with focal liver lesion...

The Association Between Hepatocellular Carcinoma and Gastrointestinal Adenocarcinoma: Is This a New Syndrome in Patients With Cirrhosis? A Case Series.

Cancer reports (Hoboken, N.J.)
AIM: This case series aimed to explore the occurrence of synchronous hepatocellular carcinoma (HCC) and gastrointestinal adenocarcinoma in cirrhotic patients and to propose a potential common pathogenic mechanism.