PURPOSE: Currently, chemoimmunotherapy is effective only in a subset of patients with advanced non-squamous non-small cell lung cancer. Robust biomarkers for predicting the efficacy of chemoimmunotherapy would be useful to identify patients who would...
Non-small cell lung cancer (NSCLC) exhibits a comparatively slower rate of metastasis in contrast to small cell lung cancer, contributing to approximately 85% of the global patient population. In this work, leveraging CT scan images, we deploy a know...
BACKGROUND: Radiation-induced pneumonitis affects up to 33% of non-small cell lung cancer (NSCLC) patients, with fatal pneumonitis occurring in 2% of patients. Pneumonitis risk is related to the dose and volume of lung irradiated. Clinical radiothera...
BACKGROUND: Multiple first-line treatment options have been developed for advanced non-small cell lung cancer (NSCLC) in each subgroup determined by predictive biomarkers, specifically driver oncogene and programmed cell death ligand-1 (PD-L1) status...
BMC medical informatics and decision making
39558294
BACKGROUND: Lung cancer is characterized by high morbidity and mortality due to the lack of practical early diagnostic and prognostic tools. The present study uses machine learning algorithms to construct a clinical predictive model for non-small cel...
Computer methods and programs in biomedicine
39551025
BACKGROUND AND OBJECTIVES: The aim of this study is to develop a radiomic and deep learning-based signature for survival analysis of patients with Non-Small Cell Lung Cancer.
BACKGROUND: Accurate prognostication of overall survival (OS) for non-small cell lung cancer (NSCLC) patients receiving definitive radiotherapy (RT) is crucial for developing personalized treatment strategies. This study aims to construct an interpre...
Laboratory investigation; a journal of technical methods and pathology
39542104
Lung squamous cell carcinoma (LUSC), a subtype of non-small cell lung cancer, represents a significant portion of lung cancer cases with distinct histologic patterns impacting prognosis and treatment. The current pathological assessment methods face ...
International journal of medical informatics
39515045
OBJECTIVES: The objective of this study is to develop a novel multi-task learning approach with attention encoders for classifying histologic subtypes and clinical stages of non-small cell lung cancer (NSCLC), with superior performance compared to cu...
BACKGROUND: Despite decades of pursuing health equity, racial and ethnic disparities persist in healthcare in America. For cancer specifically, one of the leading observed disparities is worse mortality among non-Hispanic Black patients compared to n...