AIMC Topic: Case-Control Studies

Clear Filters Showing 121 to 130 of 871 articles

HiDDEN: a machine learning method for detection of disease-relevant populations in case-control single-cell transcriptomics data.

Nature communications Nov 2, 2024
In case-control single-cell RNA-seq studies, sample-level labels are transferred onto individual cells, labeling all case cells as affected, when in reality only a small fraction of them may actually be perturbed. Here, using simulations, we demonstr...
Multiple Myeloma RNA-Seq Mice Computational Biology Humans Machine Learning Blood-Brain Barrier Animals Gene Expression Profiling Transcriptome Case-Control Studies Single-Cell Analysis
View on PubMed DOI

Screening biomarkers for autism spectrum disorder using plasma proteomics combined with machine learning methods.

Clinica chimica acta; international journal of clinical chemistry Oct 29, 2024
BACKGROUND AND AIMS: Autism spectrum disorder (ASD) is a common neurodevelopmental disorder in children. Early intervention is effective. Investigation of novel blood biomarkers of ASD facilitates early detection and intervention.
Male Case-Control Studies Child, Preschool Child Biomarkers Autism Spectrum Disorder Female Proteomics Humans Machine Learning
View on PubMed DOI

A machine learning tool for identifying newly diagnosed heart failure in individuals with known diabetes in primary care.

ESC heart failure Oct 20, 2024
AIMS: We aimed to create a predictive model utilizing machine learning (ML) to identify new cases of congestive heart failure (CHF) in individuals with diabetes in primary health care (PHC) through the analysis of diagnostic data.
Female Risk Factors Aged Adult Humans Machine Learning Retrospective Studies Primary Health Care Male Diabetes Mellitus Middle Aged Follow-Up Studies Case-Control Studies Heart Failure
View on PubMed DOI

Role of Artificial intelligence model in prediction of low back pain using T2 weighted MRI of Lumbar spine.

F1000Research Oct 10, 2024
BACKGROUND: Low back pain (LBP), the primary cause of disability, is the most common musculoskeletal disorder globally and the primary cause of disability. Magnetic resonance imaging (MRI) studies are inconclusive and less sensitive for identifying a...
Adult Male Machine Learning Humans Middle Aged Prospective Studies Magnetic Resonance Imaging Artificial Intelligence Case-Control Studies Female Lumbar Vertebrae Low Back Pain
View on PubMed DOI

Peripheral Blood Mononuclear Cell Biomarkers for Major Depressive Disorder: A Transcriptomic Approach.

Depression and anxiety Oct 3, 2024
Major depressive disorder (MDD) is a complex condition characterized by persistent depressed mood, loss of interest or pleasure, loss of energy or fatigue, and, in severe case, recurrent thoughts of death. Despite its prevalence, reliable diagnostic...
Depressive Disorder, Major Adult Gene Expression Profiling TRPV Cation Channels Humans Male Transcriptome Case-Control Studies Biomarkers Middle Aged Female Leukocytes, Mononuclear
View on PubMed DOI

Machine learning based analysis of single-cell data reveals evidence of subject-specific single-cell gene expression profiles in acute myeloid leukaemia patients and healthy controls.

Biochimica et biophysica acta. Gene regulatory mechanisms Oct 2, 2024
Acute Myeloid Leukaemia (AML) is characterized by uncontrolled growth of immature myeloid cells, disrupting normal blood production. Treatment typically involves chemotherapy, targeted therapy, and stem cell transplantation but many patients develop ...
Gene Expression Profiling Transcriptome Case-Control Studies Single-Cell Analysis Gene Expression Regulation, Leukemic Humans Machine Learning Leukemia, Myeloid, Acute
View on PubMed DOI

Molecular profiling of blood plasma-derived extracellular vesicles derived from Duchenne muscular dystrophy patients through integration of FTIR spectroscopy and machine learning reveals disease signatures.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Oct 1, 2024
PURPOSE: To identify and monitor the FTIR spectral signatures of plasma extracellular vesicles (EVs) from Duchenne Muscular Dystrophy (DMD) patients at different stages with Healthy controls using machine learning models.
Muscular Dystrophy, Duchenne Extracellular Vesicles Spectroscopy, Fourier Transform Infrared Principal Component Analysis Humans Machine Learning Case-Control Studies Biomarkers Adolescent Male Child ROC Curve
View on PubMed DOI

Convolutional neural network based detection of early stage Parkinson's disease using the six minute walk test.

Scientific reports Sep 30, 2024
The heterogeneity of Parkinson's disease (PD) presents considerable challenges for accurate diagnosis, particularly during early-stage disease, when the symptoms may be extremely subtle. This study aimed to assess the accuracy of a convolutional neur...
Parkinson Disease Walking Gait Walk Test Middle Aged Case-Control Studies Wearable Electronic Devices Neural Networks, Computer Female Aged Male Humans
View on PubMed DOI

Identification of Bipolar Disorder and Schizophrenia Based on Brain CT and Deep Learning Methods.

Journal of imaging informatics in medicine Sep 26, 2024
With the increasing prevalence of mental illness, accurate clinical diagnosis of mental illness is crucial. Compared with MRI, CT has the advantages of wide application, low price, short scanning time, and high patient cooperation. This study aims to...
Humans Brain Tomography, X-Ray Computed Case-Control Studies Deep Learning Bipolar Disorder Schizophrenia Female Adult Male Middle Aged
View on PubMed DOI

Influence of panic disorder and paroxetine on brain functional hubs in drug-free patients.

Journal of psychopharmacology (Oxford, England) Sep 23, 2024
BACKGROUND: The effects of panic disorder (PD) and pharmacotherapy on brain functional hubs in drug-free patients, and the utility of their degree centrality (DC) in diagnosing and predicting treatment response (TR) for PD, remained unclear.
Humans Brain Female Young Adult Adult Male Middle Aged Magnetic Resonance Imaging Paroxetine Case-Control Studies Selective Serotonin Reuptake Inhibitors Treatment Outcome Panic Disorder Support Vector Machine
View on PubMed DOI
Popular Topics
Recent Journals