AIMC Topic: Case-Control Studies

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Detecting knee osteoarthritis and its discriminating parameters using random forests.

Medical engineering & physics
This paper tackles the problem of automatic detection of knee osteoarthritis. A computer system is built that takes as input the body kinetics and produces as output not only an estimation of presence of the knee osteoarthritis, as previously done in...

Kinesthetic deficits after perinatal stroke: robotic measurement in hemiparetic children.

Journal of neuroengineering and rehabilitation
BACKGROUND: While sensory dysfunction is common in children with hemiparetic cerebral palsy (CP) secondary to perinatal stroke, it is an understudied contributor to disability with limited objective measurement tools. Robotic technology offers the po...

Relational-Regularized Discriminative Sparse Learning for Alzheimer's Disease Diagnosis.

IEEE transactions on cybernetics
Accurate identification and understanding informative feature is important for early Alzheimer's disease (AD) prognosis and diagnosis. In this paper, we propose a novel discriminative sparse learning method with relational regularization to jointly p...

Raman spectroscopy and PCA-SVM as a non-invasive diagnostic tool to identify and classify qualitatively glycated hemoglobin levels in vivo.

Journal of biophotonics
In this study we identify and classify high and low levels of glycated hemoglobin (HbA1c) in healthy volunteers (HV) and diabetic patients (DP). Overall, 86 subjects were evaluated. The Raman spectrum was measured in three anatomical regions of the b...

ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.

The Kaohsiung journal of medical sciences
A disintegrin-like and metalloproteinase domain with thrombospondin-type 1 motifs (ADAMTS) protein superfamily includes 19 secreted metalloproteases. Proteolytic substrates of ADAMTS enzymes have been linked to reproductive function. The aim of this ...

A novel microchip electrophoresis-based chemiluminescence immunoassay for the detection of alpha-fetoprotein in human serum.

Talanta
A sensitive immunoassay method based on microchip electrophoresis chemiluminescence (MCE-CL) detection technology was developed for the detection of tumor marker alpha-fetoprotein (AFP). This method adopts the non-competitive immunoassay mode, and wa...

Improving diagnostic recognition of primary hyperparathyroidism with machine learning.

Surgery
BACKGROUND: Parathyroidectomy offers the only cure for primary hyperparathyroidism, but today only 50% of primary hyperparathyroidism patients are referred for operation, in large part, because the condition is widely under-recognized. The diagnosis ...