AIMC Topic: Cholesterol, HDL

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Correlation between atherogenic index of plasma and retinal vessels in the fundus: a cross-sectional study.

European journal of medical research
BACKGROUND: The Atherogenic Index of Plasma (AIP) is a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol (HDL-C) concentrations and is associated with the burden of atherosclerosis. Currently, the non...

Investigating the relationship between blood factors and HDL-C levels in the bloodstream using machine learning methods.

Journal of health, population, and nutrition
INTRODUCTION: The study investigates the relationship between blood lipid components and metabolic disorders, specifically high-density lipoprotein cholesterol (HDL-C), which is crucial for cardiovascular health. It uses logistic regression (LR), dec...

Association between atherogenic index of plasma and hypertension combined with diabetes mellitus in United States adults: an analysis of the NHANES surveys from 2011 to 2016.

Journal of health, population, and nutrition
INTRODUCTION: Observational studies have indicated that individuals with hypertension (HTN) and diabetes mellitus (DM) tend to exhibit elevated plasma atherogenic index of plasma (AIP), defined as log (triglyceride [TG]/high-density lipoprotein chole...

IDENTIFYING A SEPSIS SUBPHENOTYPE CHARACTERIZED BY DYSREGULATED LIPOPROTEIN METABOLISM USING A SIMPLIFIED CLINICAL DATA ALGORITHM.

Shock (Augusta, Ga.)
Background: Cholesterol metabolism is dysregulated in sepsis contributing to patient heterogeneity. Subphenotypes displaying lower lipoprotein levels and higher mortality (previously subphenotyped hypolipoprotein phenotype [HYPO]) or higher lipoprote...

Machine learning for predicting metabolic-associated fatty liver disease including NHHR: a cross-sectional NHANES study.

PloS one
OBJECTIVE: Metabolic - associated fatty liver disease (MAFLD) is a common hepatic disorder with increasing prevalence, and early detection remains inadequately achieved. This study aims to explore the relationship between the non-high-density lipopro...

Surrogate markers of insulin resistance and coronary artery disease in type 2 diabetes: U-shaped TyG association and insights from machine learning integration.

Lipids in health and disease
BACKGROUND: Surrogate insulin resistance (IR) indices are simpler and more practical alternatives to insulin-based IR indicators for clinical use. This study explored the association between surrogate IR indices, including triglyceride-glucose index ...

Prediction of insulin resistance using multiple adaptive regression spline in Chinese women.

Endocrine journal
Insulin resistance (IR) is the core for type 2 diabetes and metabolic syndrome. The homeostasis assessment model is a straightforward and practical tool for quantifying insulin resistance (HOMA-IR). Multiple adaptive regression spline (MARS) is a mac...

A machine learning analysis of predictors of future hypertension in a young population.

Minerva cardiology and angiology
BACKGROUND: Early diagnosis of hypertension (HT) is crucial for preventing end-organ damage. This study aims to identify the risk factors for future HT in young individuals through the application of machine learning (ML) models.

Estimation of low-density lipoprotein cholesterol levels using machine learning.

International journal of cardiology
BACKGROUND: Low-density lipoprotein-cholesterol (LDL-C) is used as a threshold and target for treating dyslipidemia. Although the Friedewald equation is widely used to estimate LDL-C, it has been known to be inaccurate in the case of high triglycerid...