AIMC Topic: Cohort Studies

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Development of robust artificial neural networks for prediction of 5-year survival in bladder cancer.

Urologic oncology
PURPOSE: When exploring survival outcomes for patients with bladder cancer, most studies rely on conventional statistical methods such as proportional hazards models. Given the successful application of machine learning to handle big data in many dis...

Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning.

Gastroenterology
BACKGROUND & AIMS: Microsatellite instability (MSI) and mismatch-repair deficiency (dMMR) in colorectal tumors are used to select treatment for patients. Deep learning can detect MSI and dMMR in tumor samples on routine histology slides faster and le...

Deep-Learning F-FDG Uptake Classification Enables Total Metabolic Tumor Volume Estimation in Diffuse Large B-Cell Lymphoma.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Total metabolic tumor volume (TMTV), calculated from F-FDG PET/CT baseline studies, is a prognostic factor in diffuse large B-cell lymphoma (DLBCL) whose measurement requires the segmentation of all malignant foci throughout the body. No consensus cu...

Automatic multilabel electrocardiogram diagnosis of heart rhythm or conduction abnormalities with deep learning: a cohort study.

The Lancet. Digital health
BACKGROUND: Market-applicable concurrent electrocardiogram (ECG) diagnosis for multiple heart abnormalities that covers a wide range of arrhythmias, with better-than-human accuracy, has not yet been developed. We therefore aimed to engineer a deep le...

Leisure time physical activity is associated with improved HDL functionality in high cardiovascular risk individuals: a cohort study.

European journal of preventive cardiology
AIMS: Physical activity has consistently been shown to improve cardiovascular health and high-density lipoprotein-cholesterol levels. However, only small and heterogeneous studies have investigated the effect of exercise on high-density lipoprotein f...