AIMC Topic: Computational Biology
Clear Filters Showing 21 to 30 of 4243 articles
Identification of aging-related biomarkers and immune infiltration analysis in renal stones by integrated bioinformatics analysis.
Scientific reports
Jul 1, 2025
Renal stones (RS) are common urologic condition with unclear pathogenesis. Role of aging-related differentially expressed genes (ARDEGs) in RS remains poorly understood. This study aims to identify potential aging-related biomarkers for RS, explore t...
RiNALMo: general-purpose RNA language models can generalize well on structure prediction tasks.
Nature communications
Jul 1, 2025
While RNA has recently been recognized as an interesting small-molecule drug target, many challenges remain to be addressed before we take full advantage of it. This emphasizes the necessity to improve our understanding of its structures and function...
Deep generalizable prediction of RNA secondary structure via base pair motif energy.
Nature communications
Jul 1, 2025
Deep learning methods have demonstrated great performance for RNA secondary structure prediction. However, generalizability is a common unsolved issue on unseen out-of-distribution RNA families, which hinders further improvement of the accuracy and r...
Spatial domain detection using contrastive self-supervised learning for spatial multi-omics technologies.
Genome research
Jul 1, 2025
Recent advances in spatially resolved single-omic and multi-omics technologies have led to the emergence of computational tools to detect and predict spatial domains. Additionally, histological images and immunofluorescence (IF) staining of proteins ...
A fast (CNN + MCWS-transformer) based architecture for protein function prediction.
Statistical applications in genetics and molecular biology
Jul 1, 2025
The transformer model for sequence mining has brought a paradigmatic shift to many domains, including biological sequence mining. However, transformers suffer from quadratic complexity, i.e., O( ), where is the sequence length, which affects the tra...
rbpTransformer: A novel deep learning model for prediction of piRNA and mRNA bindings.
PloS one
Jun 25, 2025
An important issue in biotechnology is predicting whether a piRNA and an mRNA will or will not bind. Research and treatment of diseases, drug discovery, and the silencing and regulation of genes, transposons, and genomic stability may all benefit fro...
DeepRice6mA: A convolutional neural network approach for 6mA site prediction in the rice Genome.
PloS one
Jun 18, 2025
As one of the most critical post-replication modifications, N6-methylation (6mA) at adenine residue plays an important role in a variety of biological functions. Existing computational methods for identifying 6mA sites across large genomic regions te...
Next-generation cancer therapeutics: unveiling the potential of liposome-based nanoparticles through bioinformatics.
Mikrochimica acta
Jun 16, 2025
Cancer remains one of the most deadly diseases in the world, requiring constant growth and improvements in therapeutic strategies. Traditional cancer treatments, such as chemotherapy, radiotherapy, and surgery, have limitations like off-target releas...
AbEpiTope-1.0: Improved antibody target prediction by use of AlphaFold and inverse folding.
Science advances
Jun 13, 2025
B cell epitope prediction tools are crucial for designing vaccines and disease diagnostics. However, predicting which antigens a specific antibody binds to and their exact binding sites (epitopes) remains challenging. Here, we present AbEpiTope-1.0, ...
Noise-Consistent Hypergraph Autoencoder Based on Contrastive Learning for Cancer ceRNA Association Prediction in Complex Biological Regulatory Networks.
Journal of chemical information and modeling
Jun 12, 2025
Competitive endogenous RNA (ceRNA) regulatory networks (CENA) have advanced our understanding of noncoding RNAs' roles in complex diseases, providing a theoretical basis for disease mechanisms. Existing ceRNA-disease association prediction methods ar...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31088
- Neural Networks, Computer 29743
- Algorithms 26874
- Deep Learning 26387
- Artificial Intelligence 24329
- Robotics 13315
- Image Processing, Computer-Assisted 9536
- Retrospective Studies 9125
- Magnetic Resonance Imaging 6192
- Reproducibility of Results 5600
- Tomography, X-Ray Computed 4772
- Support Vector Machine 4692
- Computational Biology 4243
- Brain 4053
- Computer Simulation 3885
Recent Journals
- Scientific reports 6015
- Sensors (Basel, Switzerland) 4794
- PloS one 4029
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1864
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1133
- Journal of chemical information and modeling 1003
- Nature communications 952
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 862
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 828