AIMC Topic: Coronary Disease

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Classification of Patients with Coronary Microvascular Dysfunction.

IEEE/ACM transactions on computational biology and bioinformatics
While coronary microvascular dysfunction (CMD) is a major cause of ischemia, it is very challenging to diagnose due to lack of CMD-specific screening measures. CMD has been identified as one of the five priority areas of investigation in a 2014 Natio...

Effect of Tube Voltage on Diagnostic Performance of Fractional Flow Reserve Derived From Coronary CT Angiography With Machine Learning: Results From the MACHINE Registry.

AJR. American journal of roentgenology
Coronary CT angiography (CCTA)-based methods allow noninvasive estimation of fractional flow reserve (cFFR), recently through use of a machine learning (ML) algorithm (cFFR). However, attenuation values vary according to the tube voltage used, and i...

Constipation and risk of death and cardiovascular events.

Atherosclerosis
BACKGROUND AND AIMS: Constipation is one of the most frequent symptoms encountered in daily clinical practice and is implicated in the development of atherosclerosis, potentially through altered gut microbiota. However, little is known about its asso...

Bimodal fuzzy analytic hierarchy process (BFAHP) for coronary heart disease risk assessment.

Journal of biomedical informatics
Rooted deeply in medical multiple criteria decision-making (MCDM), risk assessment is very important especially when applied to the risk of being affected by deadly diseases such as coronary heart disease (CHD). CHD risk assessment is a stochastic, u...

Melatonin administration lowers biomarkers of oxidative stress and cardio-metabolic risk in type 2 diabetic patients with coronary heart disease: A randomized, double-blind, placebo-controlled trial.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND & AIMS: Melatonin may benefit diabetic people with coronary heart disease (CHD) through its beneficial effects on biomarkers of oxidative stress and cardio-metabolic risk. This investigation evaluated the effects of melatonin administratio...

Impact of renal impairment on platelet reactivity and clinical outcomes during chronic dual antiplatelet therapy following coronary stenting.

European heart journal. Cardiovascular pharmacotherapy
AIMS: Clinical utilization of dual antiplatelet therapy (DAPT) in patients with renal impairment (RI) following percutaneous coronary interventions (PCI) represents an urgent, unmet need choosing optimal agents, duration of treatment, and potential d...

A deep learning model could screen for coronary heart disease from a "pseudo-normal" electrocardiogram.

Medicine
BACKGROUND: This study aimed to develop a deep learning model (DLM) for rapid screening of coronary heart disease (CHD) using "pseudo-normal" electrocardiograms (ECGs), particularly focusing on patients who present with normal or near-normal ECGs at ...

Machine Learning for the Prediction of Acute Kidney Injury in Critically Ill Patients With Coronary Heart Disease: Algorithm Development and Validation.

JMIR medical informatics
BACKGROUND: Acute kidney injury (AKI) frequently occurs in critically ill patients with coronary heart disease (CHD), and its development markedly elevates mortality rates and prolongs hospitalization duration. Early AKI prediction is crucial for tim...

Prediction of coronary heart disease based on klotho levels using machine learning.

Scientific reports
The diagnostic accuracy for coronary heart disease (CHD) needs to be improved. Some studies have indicated that klotho protein levels upon admission comprise an independent risk factor for CHD and have clinical value for predicting CHD. This study ai...