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Comparison of AI chatbot predicted and realworld survival outcomes in hepatocellular carcinoma.

Scientific reports
This study compares survival predictions made by an artificial intelligence (AI) based chatbot with real-world data in hepatocellular carcinoma (HCC) patients. It aims to evaluate the reliability and accuracy of AI technologies in HCC prognosis. A re...

Evaluation of MRI-based synthetic CT for lumbar degenerative disease: a comparison with CT.

Scientific reports
Patients with lumbar degenerative disease typically undergo preoperative MRI combined with CT scans, but this approach introduces additional ionizing radiation and examination costs. To compare the effectiveness of MRI-based synthetic CT (sCT) in dis...

Metabolomic biomarkers could be molecular clocks in timing stroke onset.

Scientific reports
The preferred treatment for acute ischaemic stroke (AIS) is intravenous thrombolysis (IVT) administered within 4.5 hours (h) of symptom onset. This study aimed to identify metabolomic biomarkers for distinguishing AIS patients within 4.5 h of symptom...

Beyond accuracy: a framework for evaluating algorithmic bias and performance, applied to automated sleep scoring.

Scientific reports
Recent advancements in artificial intelligence (AI) have significantly improved sleep-scoring algorithms, bringing their performance close to the theoretical limit of approximately 80%, which aligns with inter-scorer agreement levels. While this sugg...

AI-based CT assessment of 3117 vertebrae reveals significant sex-specific vertebral height differences.

Scientific reports
Predicting vertebral height is complex due to individual factors. AI-based medical imaging analysis offers new opportunities for vertebral assessment. Thereby, these novel methods may contribute to sex-adapted nomograms and vertebral height predictio...

A novel UHPLC-HRMS method for simultaneous determination of 20 amino metabolites and proteins in lymphoma patients' cells and serum.

Scientific reports
Highly sensitive and selective monitoring of amino metabolites such as glutamine, arginine, tryptophan and related proteins played significant roles in early diagnosis and warning of lymphoma. But those limited abundance and lacked chromophore group ...

Brain structural features with functional priori to classify Parkinson's disease and multiple system atrophy using diagnostic MRI.

Scientific reports
Clinical two-dimensional (2D) MRI data has seen limited application in the early diagnosis of Parkinson's disease (PD) and multiple system atrophy (MSA) due to quality limitations, yet its diagnostic and therapeutic potential remains underexplored. T...

Radiomics analysis based on dynamic contrast-enhanced MRI for predicting early recurrence after hepatectomy in hepatocellular carcinoma patients.

Scientific reports
This study aimed to develop a machine learning model based on Magnetic Resonance Imaging (MRI) radiomics for predicting early recurrence after curative surgery in patients with hepatocellular carcinoma (HCC).A retrospective analysis was conducted on ...

Machine learning and transformer models for prediction of postoperative pneumonia risk in patients with lower limb fractures.

Scientific reports
Postoperative pneumonia, a prevalent complication arising from lower limb fracture surgery, can significantly prolong hospitalization periods and elevate mortality rates. Consequently, early prevention and identification of this condition are crucial...

Mitochondrial haplogroup A2 is associated with increased COVID-19 mortality in an admixed Brazilian population.

Scientific reports
Mitochondria play a crucial role in cellular respiration and immune responses. Mitochondrial DNA (mtDNA) haplogroups and variants have been associated with various diseases, including COVID-19. This study analyzed complete mtDNA sequences from 467 Br...