AIMC Topic: Female

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Estimating wage disparities using foundation models.

Proceedings of the National Academy of Sciences of the United States of America
The rise of foundation models marks a paradigm shift in machine learning: instead of training specialized models from scratch, foundation models are trained on massive datasets before being adjusted or fine-tuned to make predictions on smaller datase...

Prediction of Lymph Node Metastasis in Non-Small Cell Lung Carcinoma Using Primary Tumor Somatic Mutation Data.

JCO clinical cancer informatics
PURPOSE: Lymph node metastasis (LNM) significantly affects prognosis and treatment strategies in non-small cell lung cancer (NSCLC). Current diagnostic methods, including imaging and histopathology, have limited sensitivity and specificity. This stud...

Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay.

Molecular medicine (Cambridge, Mass.)
BACKGROUND: Cervical cancer screening programs are increasingly relying on sensitive molecular approaches as primary tests to detect high-risk human papillomaviruses (hrHPV), the causative agents of cervix cancer. Although hrHPV infection is a pre-re...

Clinical, genetic, and sociodemographic predictors of symptom severity after internet-delivered cognitive behavioural therapy for depression and anxiety.

BMC psychiatry
BACKGROUND: Internet-delivered cognitive behavioural therapy (ICBT) is an effective and accessible treatment for mild to moderate depression and anxiety disorders. However, up to 50% of patients do not achieve sufficient symptom relief. Identifying p...

Personalized medication recommendations for Parkinson's disease patients using gated recurrent units and SHAP interpretability.

Scientific reports
Managing Parkinson's disease (PD) through medication can be challenging due to varying symptoms and disease duration. This study aims to demonstrate the potential of sequence-by-sequence algorithms in recommending personalized medication combinations...

Effect of visceral fat on onset of metabolic syndrome.

Scientific reports
This study analysed the effects of visceral fat on metabolic syndrome (MetS) and developed an algorithm to predict its onset using health examination data from the Iwaki Health Promotion Project in Japan. The dataset included 213 cases of MetS onset ...

Upper limb human-exoskeleton system motion state classification based on semg: application of CNN-BiLSTM-attention model.

Scientific reports
This study aims to classify five typical motion states of the human upper limb based on surface electromyography signals, thereby supporting the real-time control system of an assistive upper limb exoskeleton. We propose a deep learning model combini...

Integrated plasma and vegetation proteomic characterization of infective endocarditis for early diagnosis and treatment.

Nature communications
Infective endocarditis, a life-threatening condition, poses challenges for early diagnosis and personalized treatment due to insufficient biomarkers and limited understanding of its pathophysiology. Here, we performed proteomic profiling of plasma an...

Development and validation of the Immune Profile Score (IPS), a novel multiomic algorithmic assay for stratifying outcomes in a real-world cohort of patients with advanced solid cancer treated with immune checkpoint inhibitors.

Journal for immunotherapy of cancer
BACKGROUND: Immune checkpoint inhibitors (ICIs) have transformed the oncology treatment landscape. Despite substantial improvements for some patients, the majority do not benefit from ICIs, indicating a need for predictive biomarkers to better inform...