AIMC Topic: Female
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Metabolic profiles in laryngeal cancer defined two distinct molecular subtypes with divergent prognoses.
Frontiers in immunology
May 22, 2025
BACKGROUND: Laryngeal cancer (LCA) is the second most common type of head and neck malignancy, characterized by high recurrence rates and poor overall survival (OS). However, progress in curing LCA through molecular-targeted diagnostics and therapies...
Single-cell and bulk transcriptome analyses reveal elevated amino acid metabolism promoting tumor-directed immune evasion in colorectal cancer.
Frontiers in immunology
May 22, 2025
INTRODUCTION: Colorectal cancer (CRC), the third most common cancer worldwide, often shows limited responsiveness to immunotherapy due to its predominantly immune-excluded phenotype. Despite increasing insights into the complex tumor microenvironment...
Tumor Escape
Gene Expression Profiling
Transcriptome
Cell Line, Tumor
Single-Cell Analysis
CD8-Positive T-Lymphocytes
Colorectal Neoplasms
Humans
Gene Expression Regulation, Neoplastic
Prognosis
Amino Acids
Tumor Microenvironment
Female
Lymphocytes, Tumor-Infiltrating
Programmed Cell Death 1 Receptor
Male
Fidelity to territory and mate and the causes and consequences of breeding dispersal in American goshawk (Astur atricapillus).
PloS one
May 22, 2025
Using mark-resight data, we investigated fidelity to territory and mate as well as breeding dispersal rates and the causes and consequences of breeding dispersal in a 20-year study of American goshawks (Astur atricapillus) in Arizona, USA. Generalize...
Influence of the CONCERN Early Warning System on Unanticipated ICU Transfers, In-Hospital Mortality, and Length of Stay: Results from a Multi-site Pragmatic Randomized Controlled Clinical Trial.
AMIA ... Annual Symposium proceedings. AMIA Symposium
May 22, 2025
Communicating Narrative Concerns Entered by RNs Early Warning System (CONCERN EWS) is a machine-learning predictive model that leverages nursing surveillance documentation patterns to predict deterioration risks for hospitalized patients. In a retros...
Meta-analysis of shotgun sequencing of gut microbiota in obese children with MASLD or MASH.
Gut microbes
May 21, 2025
Alterations in the gut microbiome affect the development and severity of metabolic dysfunction-associated steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). We analyzed microbiomes of obese children with and w...
Performance of multimodal prediction models for intracerebral hemorrhage outcomes using real-world data.
International journal of medical informatics
May 21, 2025
BACKGROUND: We aimed to develop and validate multimodal models integrating computed tomography (CT) images, text and tabular clinical data to predict poor functional outcomes and in-hospital mortality in patients with intracerebral hemorrhage (ICH). ...
Preterm birth trends and risk factors in a multi-ethnic Asian population: A retrospective study from 2017 to 2023, can we screen and predict this?
Annals of the Academy of Medicine, Singapore
May 21, 2025
INTRODUCTION: Preterm birth (PTB) remains a leading cause of perinatal morbidity and mortality worldwide. Understanding Singapore's PTB trends and associated risk factors can inform effective strategies for screening and intervention. This study anal...
Harnessing Fast Fourier Transform for Rapid Community Travel Distance and Step Estimation in Children with Duchenne Muscular Dystrophy.
Sensors (Basel, Switzerland)
May 21, 2025
Accurate estimation of gait characteristics, including step length, step velocity, and travel distance, is critical for assessing mobility in toddlers, children, and teens with Duchenne muscular dystrophy (DMD) and typically developing (TD) peers. Th...
Establishment of a prognostic model based on ER stress-related cell death genes and proposing a novel combination therapy in acute myeloid leukemia.
Journal of translational medicine
May 21, 2025
BACKGROUND: Acute myeloid leukemia (AML) is a highly heterogeneous malignancy, presenting significant challenges in accurately predicting patient prognosis. Dysregulation of endoplasmic reticulum (ER) stress and resistance to programmed cell death (P...
Association between atherogenicity indices and prediabetes: a 5-year retrospective cohort study in a general Chinese physical examination population.
Cardiovascular diabetology
May 21, 2025
BACKGROUND AND OBJECTIVE: Atherogenicity indices have emerged as promising markers for cardiometabolic disorders, yet their relationship with prediabetes risk remains unclear. This study aimed to comprehensively evaluate the associations between six ...
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