Colorectal cancer (CRC) exhibits substantial heterogeneity in molecular subtypes and clinical outcomes. We performed an integrative analysis of multi-omics data from 274 CRC patients to investigate the impact of gut microbiota composition on prognosi...
Right ventricular dysfunction (RVD) is strongly associated with increased mortality in patients with acute pulmonary embolism (PE), making its early detection crucial. Identifying RVD risk factors rapidly, accurately, and economically within the acut...
Psychosis poses substantial social and healthcare burdens. The analysis of speech is a promising approach for the diagnosis and monitoring of psychosis, capturing symptoms like thought disorder and flattened affect. Recent advancements in Natural Lan...
BACKGROUND: Glioma is characterized by a poor prognosis and limited possibilities for treatment. Previous studies have developed prediction models for glioma using genetic, clinical, pathological, imaging and other aspects; however, few studies have ...
BACKGROUND: Lower pole renal stones (LPS) present unique challenges for retrograde intrarenal surgery (RIRS) due to unfavorable anatomical features, often resulting in suboptimal stone-free rates (SFR). Recent advancements in machine learning (ML) of...
BACKGROUND: Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most common cause of cancer-related death. Cirrhosis is a major contributing factor, accounting for over 90% of HCC cases. With the high mortality rate...
Social anxiety disorder (SAD) is a prevalent psychiatric condition with significant psychological and socioeconomic consequences. While its psychological characteristics are well-documented, the underlying molecular mechanisms remain poorly understoo...
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Jul 11, 2025
Despite advances in the treatment of major depressive disorder (MDD) yet a substantial proportion of patients fail to achieve remission and instead develop treatment-resistant depression (TRD). Identifying robust clinical predictors of response is es...
Identification of Alzheimer's Disease (AD), especially in its early phases, presents significant challenges due to the nonexistence of reliable biomarkers and effective treatments. Clinical trials for AD medications also suffer from high failure rate...
Detecting driver drowsiness through electroencephalogram (EEG) poses challenges due to the complexity and variability of brain activity across different subjects. This study proposes a feature extraction pipeline combined with a Long Short-Term Memor...
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