OBJECTIVE: The medical community recently experienced a severe shortage of blood culture media bottles. Rates of blood stream infection (BSI) among critically ill children are low. We sought to design a machine learning (ML) model able to identify ch...
Proteomic studies have been instrumental in identifying brain, cerebrospinal fluid and plasma proteins associated with Alzheimer's disease (AD). Here, we comprehensively examined 6,905 aptamers corresponding to 6,106 unique proteins in plasma in more...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
The clinical benefits of neoadjuvant chemoimmunotherapy (NACI) are demonstrated in patients with bladder cancer (BCa); however, more than half fail to achieve a pathological complete response (pCR). This study utilizes multi-center cohorts of 2322 pa...
BACKGROUND: Recent advancements in digital pathology have extended into cytopathology. Laboratories screening cervical cytology specimens now choose between limited imaging options and traditional manual microscopy. The Techcyte SureView™ Cervical Cy...
Accurate and timely diagnosis of brain tumors is critical for patient management and treatment planning. Magnetic resonance imaging (MRI) is a widely used modality for brain tumor detection and characterization, often aided by the administration of g...
OBJECTIVE: Postpartum depression (PPD) is a major contributor to postpartum morbidity and mortality. Beyond efforts at routine screening, risk stratification models could enable more targeted interventions in settings with limited resources. The auth...
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Jun 1, 2025
OBJECTIVES: The resting-state cerebral functional activity underlying chronic insomnia disorder (CID) remains inconsistent, and the effects of pharmacotherapy on such activity are unclear.
The application of AI for predicting critical heart failure endpoints using echocardiography is a promising avenue to improve patient care and treatment planning. However, fully supervised training of deep learning models in medical imaging requires ...
BACKGROUND: Early identification of individuals who progress from normal cognition (NC) to mild cognitive impairment (MCI) may help prevent cognitive decline. We aimed to build predictive models using radiomic features of the bilateral hippocampus in...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jun 1, 2025
PURPOSE: Breast ultrasound (BUS) computer-aided diagnosis (CAD) systems aims to perform two major steps: detecting lesions and classifying them as benign or malignant. However, the impact of combining both steps has not been previously addressed. Mor...
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