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Deep-learning based multi-modal models for brain age, cognition and amyloid pathology prediction.

Alzheimer's research & therapy
BACKGROUND: Magnetic resonance imaging (MRI), combined with artificial intelligence techniques, has improved our understanding of brain structural change and enabled the estimation of brain age. Neurodegenerative disorders, such as Alzheimer's diseas...

Machine learning algorithms to predict stroke in China based on causal inference of time series analysis.

BMC neurology
IMPORTANCE: Identifying and managing high-risk populations for stroke in a targeted manner is a key area of preventive healthcare.

Enhanced neuroplasticity and gait recovery in stroke patients: a comparative analysis of active and passive robotic training modes.

BMC neurology
BACKGROUND: Stroke is a leading cause of long-term disability, with lower limb dysfunction being a common sequela that significantly impacts patients' mobility and quality of life. Robotic-assisted training has emerged as a promising intervention for...

Identifying the key factors of mercury exposure in residents of southwestern Iran using machine learning algorithms.

Environmental geochemistry and health
It is necessary to predict hair mercury (Hg) levels and specify the related effective factors to develop preventive strategies to reduce Hg exposure in different regions. This study is the first effort to investigate the effectiveness of eight machin...

Development and validation of an integrated residual-recurrent neural network model for automated heart murmur detection in pediatric populations.

Scientific reports
Congenital heart disease affects approximately 1% of children worldwide, with a number of cases in resource-limited settings remaining undiagnosed through school age. While cardiac auscultation is a key screening method, its effectiveness varies wide...

A machine learning-derived angiogenesis signature for clinical prognosis and immunotherapy guidance in colon adenocarcinoma.

Scientific reports
Colon adenocarcinoma (COAD) is one of the most prevalent malignancies worldwide and its prognosis is extremely poor. Angiogenesis has been linked to clinical outcomes, tumor progression, and treatment sensitivity. However, the role of angiogenesis in...

Applying machine learning with MobileNetV2 model for rapid screening of vaginal discharge samples in vaginitis diagnosis.

Scientific reports
Vaginitis is a prevalent gynecological condition that impacts women's quality of life, with most women likely to experience it at least once. Traditional diagnosis involves manually observing vaginal discharge samples under a microscope. This process...

Integrating bulk RNA-seq and scRNA-seq analyses with machine learning to predict platinum response and prognosis in ovarian cancer.

Scientific reports
Platinum-based therapy is an integral part of the standard treatment for ovarian cancer. However, despite extensive research spanning several decades, the identification of dependable predictive biomarkers for platinum response in clinical practice h...

Development and validation of a 3-D deep learning system for diabetic macular oedema classification on optical coherence tomography images.

BMJ open
OBJECTIVES: To develop and validate an automated diabetic macular oedema (DME) classification system based on the images from different three-dimensional optical coherence tomography (3-D OCT) devices.