AIMC Topic: Female

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5-5-5 ABRT (Dose of 5 Gy per Fraction for up to 5 Fractions Over 5 Weeks Adaptive Bridging Radiation Therapy)-Artificial Intelligence Enters the CAR (-T) (Chimeric Antigen Receptor-T) in Relapsed/Refractory Large B Cell Lymphoma.

International journal of radiation oncology, biology, physics
PURPOSE: Bridging radiation therapy (BRT) is effective for local control in patients with relapsed or refractory large B cell lymphoma who are undergoing chimeric antigen receptor (CAR) T cell therapy. We hypothesized that adaptive BRT (ABRT), which ...

Effects of Renal Function on the Multimodal Brain Networks Affecting Mild Cognitive Impairment Converters in End-Stage Renal Disease.

Academic radiology
RATIONALE AND OBJECTIVES: Cognitive decline is common in End-Stage Renal Disease (ESRD) patients, yet its neural mechanisms are poorly understood. This study investigates structural and functional brain network reconfiguration in ESRD patients transi...

Refining early detection of Marburg Virus Disease (MVD) in Rwanda: Leveraging predictive symptom clusters to enhance case definitions.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
BACKGROUND: Marburg Virus Disease (MVD) poses a significant global health risk due to its high case fatality rates (24%-88%) and the diagnostic challenges posed by its nonspecific early symptoms, which overlap with other febrile illnesses like malari...

Increased Global and Regional Connectivity in Propofol-induced Unconsciousness: Human Intracranial Electroencephalography Study.

Anesthesiology
BACKGROUND: The conscious state is maintained through intact communication between brain regions. However, studies on global and regional connectivity changes in unconscious state have been inconsistent. These inconsistencies could arise from unclear...

Predicting high-risk factors for postoperative inadequate analgesia and adverse reactions in cesarean delivery surgery: a prospective study.

International journal of surgery (London, England)
BACKGROUND: Early identification of high-risk factors for inadequate analgesia and adverse reactions in obstetric patients is critical for improving outcomes. This study developed a machine learning model to predict these factors and optimize anesthe...

A Tc1- and Th1-T-lymphocyte-rich tumor microenvironment is a hallmark of MSI colorectal cancer.

The Journal of pathology
Microsatellite instability is a strong predictor of response to immune checkpoint therapy and patient outcome in colorectal cancer. Although enrichment of distinct T-cell subpopulations has been determined to impact the response to immune checkpoint ...

Clinical implementation of AI-based screening for risk for opioid use disorder in hospitalized adults.

Nature medicine
Adults with opioid use disorder (OUD) are at increased risk for opioid-related complications and repeated hospital admissions. Routine screening for patients at risk for an OUD to prevent complications is not standard practice in many hospitals, lead...

A Novel Theranostic Strategy for Malignant Pulmonary Nodules by Targeted CECAM6 with Zr/I-Labeled Tinurilimab.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Lung adenocarcinoma (LUAD) constitutes a major cause of cancer-related fatalities worldwide. Early identification of malignant pulmonary nodules constitutes the most effective approach to reducing the mortality of LUAD. Despite the wide application o...

Effect of a ChatGPT-based digital counseling intervention on anxiety and depression in patients with cancer: A prospective, randomized trial.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Psychological distress is prevalent among newly diagnosed cancer patients, often exacerbating treatment-related anxiety and depression. Artificial intelligence (AI)-driven interventions, such as large language models (LLMs), offer scalabl...

Prediction of IUGR condition at birth by means of CTG recordings and a ResNet model.

Computers in biology and medicine
OBJECTIVE: Sub-optimal uterine-placental perfusion and fetal nutrition can lead to intrauterine growth restriction (IUGR), also called fetal growth restriction (FGR). Antenatal cardiotocography (CTG) can aid in the early detection of IUGR. Reliably d...