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Fluorodeoxyglucose F18

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Predicting changes in brain metabolism and progression from mild cognitive impairment to dementia using multitask Deep Learning models and explainable AI.

NeuroImage
BACKGROUND: The prediction of Alzheimer's disease (AD) progression from its early stages is a research priority. In this context, the use of Artificial Intelligence (AI) in AD has experienced a notable surge in recent years. However, existing investi...

Development and validation of a machine learning-based F-fluorodeoxyglucose PET/CT radiomics signature for predicting gastric cancer survival.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Survival prognosis of patients with gastric cancer (GC) often influences physicians' choice of their follow-up treatment. This study aimed to develop a positron emission tomography (PET)-based radiomics model combined with clinical tumor-...

GWO+RuleFit: rule-based explainable machine-learning combined with heuristics to predict mid-treatment FDG PET response to chemoradiation for locally advanced non-small cell lung cancer.

Physics in medicine and biology
Vital rules learned from fluorodeoxyglucose positron emission tomography (FDG-PET) radiomics of tumor subregional response can provide clinical decision support for precise treatment adaptation. We combined a rule-based machine learning (ML) model (R...

F-FDG PET/CT Radiomics-Based Multimodality Fusion Model for Preoperative Individualized Noninvasive Prediction of Peritoneal Metastasis in Advanced Gastric Cancer.

Annals of surgical oncology
PURPOSE: This study was designed to develop and validate a machine learning-based, multimodality fusion (MMF) model using F-fluorodeoxyglucose (FDG) PET/CT radiomics and kernelled support tensor machine (KSTM), integrated with clinical factors and nu...

Deep learning-aided respiratory motion compensation in PET/CT: addressing motion induced resolution loss, attenuation correction artifacts and PET-CT misalignment.

European journal of nuclear medicine and molecular imaging
PURPOSE: Respiratory motion (RM) significantly impacts image quality in thoracoabdominal PET/CT imaging. This study introduces a unified data-driven respiratory motion correction (uRMC) method, utilizing deep learning neural networks, to solve all th...

Deep learning with uncertainty estimation for automatic tumor segmentation in PET/CT of head and neck cancers: impact of model complexity, image processing and augmentation.

Biomedical physics & engineering express
Target volumes for radiotherapy are usually contoured manually, which can be time-consuming and prone to inter- and intra-observer variability. Automatic contouring by convolutional neural networks (CNN) can be fast and consistent but may produce unr...

An end-to-end deep learning pipeline to derive blood input with partial volume corrections for automated parametric brain PET mapping.

Biomedical physics & engineering express
Dynamic 2-[18F] fluoro-2-deoxy-D-glucose positron emission tomography (dFDG-PET) for human brain imaging has considerable clinical potential, yet its utilization remains limited. A key challenge in the quantitative analysis of dFDG-PET is characteriz...

Multimodal radiomics-based methods using deep learning for prediction of brain metastasis in non-small cell lung cancer withF-FDG PET/CT images.

Biomedical physics & engineering express
. Approximately 57% of non-small cell lung cancer (NSCLC) patients face a 20% risk of brain metastases (BMs). The delivery of drugs to the central nervous system is challenging because of the blood-brain barrier, leading to a relatively poor prognosi...