Cell death has long been a focal point in life sciences research, and recently, scientists have discovered a novel form of cell death induced by copper, termed cuproptosis. This paper aimed to identify genes associated with cuproptosis in systemic lu...
Breast cancer remains a global health burden, with an increase in deaths related to this particular cancer. Accurately predicting and diagnosing breast cancer is important for treatment development and survival of patients. This study aimed to accura...
BACKGROUND: Acute kidney injury (AKI) after kidney transplantation is one of the main causes of graft loss and poor patient prognosis, and it is important to explore new targets for treating AKI in kidney transplantation.
BACKGROUND: Diabetic retinopathy (DR) is a common complication of diabetes, with Endoplasmic reticulum stress (ERS) playing a key role in cellular adaptation, injury, or apoptosis, impacting disease pathology. This study aimed to identify early diagn...
Programmed cell death (PCD) plays a critical role in cancer biology, influencing tumor progression and treatment response. This study aims to investigate the role of PCD-related genes in hepatocellular carcinoma (HCC), identifying potential prognosti...
Asian Pacific journal of cancer prevention : APJCP
Mar 1, 2025
OBJECTIVE: Ovarian cancer's complexity and heterogeneity pose significant challenges in treatment, often resulting in suboptimal chemotherapy outcomes. This study aimed to leverage machine learning algorithms, gene selection, and gene expression dat...
BACKGROUND: Some nonfunctioning pituitary neuroendocrine tumor (NFPitNET) can show invasive growth, which increases the difficulty of surgery and indicates a poor prognosis. However, the molecular mechanism related to invasiveness remains to be furth...
Gene selection is crucial for cancer classification using microarray data. In the interests of improving cancer classification accuracy, in this paper, we developed a new wrapper method called ieGENES for gene selection. First we proposed a parsimoni...
The relationship between ischemic stroke (IS) and pyroptosis centers on the inflammatory response elicited by cerebral tissue damage during an ischemic stroke event. However, an in-depth mechanistic understanding of their connection remains limited. ...
INTRODUCTION: Knee osteoarthritis (KOA) is a degenerative joint disease characterized by the progressive deterioration of cartilage and synovial inflammation. A critical mechanism in the pathogenesis of KOA is impaired efferocytosis in synovial tissu...
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