OBJECTIVE: Subarachnoid hemorrhage (SAH) and tumorigenesis share numerous biological complexities; nevertheless, the specific gene expression profiles and underlying mechanisms remain poorly understood. This study aims to identify differentially expr...
BACKGROUND: In breast cancer, several gene expression assays have been developed to provide a more personalised treatment. This study focuses on the prediction of two molecular proliferation signatures: an 11-gene proliferation score and the MKI67 pr...
BACKGROUND: The heterogeneity of cancer makes it challenging to predict its response to immunotherapy, highlighting the need to find reliable biomarkers for assessment. The sophisticated role of cancer stemness in mediating resistance to immune check...
BACKGROUND: Abdominal aortic aneurysm (AAA) is a serious life-threatening vascular disease, and its ferroptosis/cuproptosis markers have not yet been characterized. This study was aiming to identify markers associated with ferroptosis/cuproptosis in ...
BACKGROUND: This study aimed to explore the correlation between primary tumors (PT) and paired metastatic lymph nodes (LN) and to develop a predictive model to provide evidence for forecasting patient prognoses.
BACKGROUND: MicroRNAs (miRNAs) have shown potential as diagnostic biomarkers for myocardial infarction (MI) due to their early dysregulation and stability in circulation after MI. Moreover, they play a crucial role in regulating adaptive and maladapt...
Head and neck squamous carcinoma (HNSC), characterized by a high degree of malignancy, develops in close association with the tumor immune microenvironment (TIME). Therefore, identifying effective targets related to HNSC and TIME is of paramount impo...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 10, 2024
Recent advancements in spatially transcriptomics (ST) technologies have enabled the comprehensive measurement of gene expression profiles while preserving the spatial information of cells. Combining gene expression profiles and spatial information ha...
IEEE/ACM transactions on computational biology and bioinformatics
Dec 10, 2024
Microarray data provide lots of information regarding gene expression levels. Due to the large amount of such data, their analysis requires sufficient computational methods for identifying and analyzing gene regulation networks; however, researchers ...
Large-scale gene-expression data are being leveraged to pretrain models that implicitly learn gene and cellular functions. However, such models require extensive data curation and training. Here we explore a much simpler alternative: leveraging ChatG...
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