AIMC Topic: Head and Neck Neoplasms

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The potential use of deep learning in performing autocorrection of setup errors in patients receiving radiotherapy.

Radiography (London, England : 1995)
INTRODUCTION: Modern radiotherapy practice relies on multiple approaches for verification of patient positioning. All of these techniques require experienced radiotherapists who understand the anatomical landmarks and the limitations of the used veri...

Enhancing surgical precision in squamous cell carcinoma of the head and neck: Hyperspectral imaging and artificial intelligence for improved margin assessment in an ex vivo setting.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
BACKGROUND: Head and neck cancers, constituting 3-5% of all cancer cases, often require surgical resection for optimal outcomes. Achieving complete resection (R0) is crucial, but current methods, relying on white light endoscopy and microscopy, have ...

Deep learning-based Monte Carlo dose prediction for heavy-ion online adaptive radiotherapy and fast quality assurance: A feasibility study.

Medical physics
BACKGROUND: Online adaptive radiotherapy (OART) and rapid quality assurance (QA) are essential for effective heavy ion therapy (HIT). However, there is a shortage of deep learning (DL) models and workflows for predicting Monte Carlo (MC) doses in suc...

A radiomics model combining machine learning and neural networks for high-accuracy prediction of cervical lymph node metastasis on ultrasound of head and neck squamous cell carcinoma.

Oral surgery, oral medicine, oral pathology and oral radiology
OBJECTIVE: This study aimed to develop an ultrasound image-based radiomics model for diagnosing cervical lymph node (LN) metastasis in patients with head and neck squamous cell carcinoma (HNSCC) that shows higher accuracy than previous models.

Machine learning prediction model for oral mucositis risk in head and neck radiotherapy: a preliminary study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PURPOSE: Oral mucositis (OM) reflects a complex interplay of several risk factors. Machine learning (ML) is a promising frontier in science, capable of processing dense information. This study aims to assess the performance of ML in predicting OM ris...

Evaluation of machine learning models for predicting xerostomia in adults with head and neck cancer during proton and heavy ion radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: Few studies have examined the factors associated with xerostomia during proton and carbon ion radiotherapy for head and neck cancer (HNC), which are reported to have fewer toxic effects compared to traditional photon-based rad...

Identification of genomic alteration and prognosis using pathomics-based artificial intelligence in oral leukoplakia and head and neck squamous cell carcinoma: a multicenter experimental study.

International journal of surgery (London, England)
BACKGROUND: Loss of chromosome 9p is an important biomarker in the malignant transformation of oral leukoplakia (OLK) to head and neck squamous cell carcinoma (HNSCC), and is associated with the prognosis of HNSCC patients. However, various challenge...

Identification of a gene score related to antigen processing and presentation machinery for predicting prognosis in head and neck squamous cell carcinoma and its potential implications for immunotherapy.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
BACKGROUND: Despite its crucial role in immune surveillance and cell survival of tumors, the significance of MHC antigen processing and presentation machinery (APM) is still not fully understood in head and neck squamous cell carcinoma (HNSCC). We so...

Integrating immune multi-omics and machine learning to improve prognosis, immune landscape, and sensitivity to first- and second-line treatments for head and neck squamous cell carcinoma.

Scientific reports
In recent years, immune checkpoint inhibitors (ICIs) has emerged as a fundamental component of the standard treatment regimen for patients with head and neck squamous cell carcinoma (HNSCC). However, accurately predicting the treatment effectiveness ...

Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma.

CPT: pharmacometrics & systems pharmacology
We employed a mechanistic learning approach, integrating on-treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post-progression survival (PPS)-the duration from the time of document...