AIMC Topic: Healthy Volunteers

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Machine-learned analysis of quantitative sensory testing responses to noxious cold stimulation in healthy subjects.

European journal of pain (London, England) Jan 16, 2018
BACKGROUND: Pain in response to noxious cold has a complex molecular background probably involving several types of sensors. A recent observation has been the multimodal distribution of human cold pain thresholds. This study aimed at analysing reprod...
TRPA1 Cation Channel Pain Healthy Volunteers Cold Temperature Pain Threshold Pain Perception Humans Machine Learning Female Reproducibility of Results Young Adult Adult Male Middle Aged Adolescent
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Motor modules during adaptation to walking in a powered ankle exoskeleton.

Journal of neuroengineering and rehabilitation Jan 3, 2018
BACKGROUND: Modules of muscle recruitment can be extracted from electromyography (EMG) during motions, such as walking, running, and swimming, to identify key features of muscle coordination. These features may provide insight into gait adaptation as...
Humans Young Adult Biomechanical Phenomena Male Healthy Volunteers Ankle Joint Motor Skills Exoskeleton Device Adaptation, Physiological Muscle, Skeletal Robotics Electromyography Walking Gait
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Investigation of genotoxic effects of paraben in cultured human lymphocytes.

Drug and chemical toxicology Dec 27, 2017
Paraben is a phenolic derivative of benzoic acid extensively used as preservatives in food, pharmaceutical, and cosmetic industries due to its antimicrobial characteristics. The objective of this study was to evaluate the in vitro genotoxic effects o...
Chromosome Aberrations Micronuclei, Chromosome-Defective Mitotic Index Healthy Volunteers Sister Chromatid Exchange Parabens Humans Comet Assay Cells, Cultured Mutagens Dose-Response Relationship, Drug Micronucleus Tests DNA Damage Lymphocytes
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A Feasibility Study of SSVEP-Based Passive Training on an Ankle Rehabilitation Robot.

Journal of healthcare engineering Sep 17, 2017
OBJECTIVE: This study aims to establish a steady-state visual evoked potential- (SSVEP-) based passive training protocol on an ankle rehabilitation robot and validate its feasibility.
Motion Healthy Volunteers Brain-Computer Interfaces Evoked Potentials, Visual Ankle Joint Humans Virtual Reality Ankle Algorithms Robotics Photic Stimulation Female Electroencephalography Fourier Analysis Reproducibility of Results Signal Processing, Computer-Assisted Rehabilitation Young Adult Feasibility Studies Male
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MIT-Skywalker: considerations on the Design of a Body Weight Support System.

Journal of neuroengineering and rehabilitation Sep 6, 2017
BACKGROUND: To provide body weight support during walking and balance training, one can employ two distinct embodiments: support through a harness hanging from an overhead system or support through a saddle/seat type. This paper presents a comparison...
Humans Software Female Adult Gait Disorders, Neurologic Healthy Volunteers Nervous System Diseases Walking Speed Orthotic Devices Biomechanical Phenomena Bicycling Male Robotics Walking Body Weight
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How does wearable robotic exoskeleton affect overground walking performance measured with the 10-m and six-minute walk tests after a basic locomotor training in healthy individuals?

Gait & posture Aug 26, 2017
It is still unknown to what extent overground walking with a WRE is equivalent to natural overground walking without a WRE. Hence, the interpretability of the 10-m (10MWT) and six-minute (6MWT) walk tests during overground walking with a WRE against ...
Walk Test Male Time Factors Robotics Equipment Design Walking Healthy Volunteers Locomotion Spinal Cord Injuries Exoskeleton Device Physical Therapy Modalities Humans Female Adult
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Detection of lung cancer in exhaled breath with an electronic nose using support vector machine analysis.

Journal of breath research Aug 21, 2017
Lung cancer is one of the most common malignancies and has a low 5-year survival rate. There are no cheap, simple and widely available screening methods for the early diagnostics of lung cancer. The aim of this study was to determine whether analysis...
Pulmonary Disease, Chronic Obstructive Male Middle Aged Case-Control Studies Lung Neoplasms Humans Female Aged Adult Electronic Nose Support Vector Machine Neoplasm Staging Healthy Volunteers Breath Tests Exhalation
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A Control Scheme to Minimize Muscle Energy for Power Assistant Robotic Systems Under Unknown External Perturbation.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society Jul 5, 2017
This paper proposes a novel control method to minimize muscle energy for power-assistant robotic systems that support the intended motions of a user under unknown external perturbations, using surface electromyogram (sEMG) signals. Conventional contr...
Healthy Volunteers Wrist Joint Elbow Joint Signal Processing, Computer-Assisted Electromyography Torque Humans Activities of Daily Living Algorithms Adult Biomechanical Phenomena Male Muscle, Skeletal Robotics
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KAPS (kinematic assessment of passive stretch): a tool to assess elbow flexor and extensor spasticity after stroke using a robotic exoskeleton.

Journal of neuroengineering and rehabilitation Jun 19, 2017
BACKGROUND: Spasticity is a common sequela of stroke. Traditional assessment methods include relatively coarse scales that may not capture all characteristics of elevated muscle tone. Thus, the aim of this study was to develop a tool to quantitativel...
Exoskeleton Device Stroke Rehabilitation Physical Examination Muscle Spasticity Robotics Elbow Stroke Healthy Volunteers Range of Motion, Articular Sensitivity and Specificity Female Biomechanical Phenomena Humans Aged Male Aged, 80 and over Middle Aged Young Adult Adolescent Adult
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Modifying upper-limb inter-joint coordination in healthy subjects by training with a robotic exoskeleton.

Journal of neuroengineering and rehabilitation Jun 12, 2017
BACKGROUND: The possibility to modify the usually pathological patterns of coordination of the upper-limb in stroke survivors remains a central issue and an open question for neurorehabilitation. Despite robot-led physical training could potentially ...
Humans Algorithms Female Young Adult Adult Biomechanical Phenomena Psychomotor Performance Physical Education and Training Joints Stroke Rehabilitation Movement Gravitation Male Exoskeleton Device Posture Upper Extremity Robotics Prosthesis Design Healthy Volunteers
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