AIMC Topic: Humans

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Unveiling the effect of urinary xenoestrogens on chronic kidney disease in adults: A machine learning model.

Ecotoxicology and environmental safety
Exposure to three primary xenoestrogens (XEs), including phthalates, parabens, and phenols, has been strongly associated with chronic kidney disease (CKD). An interpretable machine learning (ML) model was developed to predict CKD using data from the ...

Deep Learning-Based Tumor Segmentation of Murine Magnetic Resonance Images of Prostate Cancer Patient-Derived Xenografts.

Tomography (Ann Arbor, Mich.)
BACKGROUND/OBJECTIVE: Longitudinal in vivo studies of murine xenograft models are widely utilized in oncology to study cancer biology and develop therapies. Magnetic resonance imaging (MRI) of these tumors is an invaluable tool for monitoring tumor g...

Towards Rapid and Low-Cost Stroke Detection Using SERS and Machine Learning.

Biosensors
Stroke affects approximately 12 million individuals annually, necessitating swift diagnosis to avert fatal outcomes. Current hospital imaging protocols often delay treatment, underscoring the need for portable diagnostic solutions. We have investigat...

Content-Based Histopathological Image Retrieval.

Sensors (Basel, Switzerland)
Feature descriptors in histopathological images are an important challenge for the implementation of Content-Based Image Retrieval (CBIR) systems, an essential tool to support pathologists. Deep learning models like Convolutional Neural Networks and ...

Investigation of Trajectory Tracking Control in Hip Joints of Lower-Limb Exoskeletons Using SSA-Fuzzy PID Optimization.

Sensors (Basel, Switzerland)
The application of lower-limb exoskeleton robots in rehabilitation is becoming more prevalent, where the precision of control and the speed of response are essential for effective movement tracking. This study tackles the challenge of optimizing both...

Application of causal forests to randomised controlled trial data to identify heterogeneous treatment effects: a case study.

BMC medical research methodology
BACKGROUND: Classical approaches to subgroup analysis in randomised controlled trials (RCTs) to identify heterogeneous treatment effects (HTEs) involve testing the interaction between each pre-specified possible treatment effect modifier and the trea...

Identification of metabolite-disease associations based on knowledge graph.

Metabolomics : Official journal of the Metabolomic Society
BACKGROUND: Despite the insights that metabolite analysis can provide into the onset, development, and progression of diseases-thus offering new concepts and methodologies for prevention, diagnosis, and treatment-traditional wet lab experiments are o...

Identification of UBE2N as a biomarker of Alzheimer's disease by combining WGCNA with machine learning algorithms.

Scientific reports
Alzheimer's disease (AD) is the most common cause of dementia, emphasizing the critical need for the development of biomarkers that facilitate accurate and objective assessment of disease progression for early detection and intervention to delay its ...

Feasibility study of texture-based machine learning approach for early detection of neonatal jaundice.

Scientific reports
Untreated neonatal jaundice can have severe consequences. Effective screening for neonatal jaundice can prevent long-term complications in infants. Non-invasive approaches may be beneficial in settings with limited resources. This feasibility study e...

Spatial recognition and semi-quantification of epigenetic events in pancreatic cancer subtypes with multiplexed molecular imaging and machine learning.

Scientific reports
Genomic alterations are the driving force behind pancreatic cancer (PC) tumorigenesis, but they do not fully account for its diverse phenotypes. Investigating the epigenetic landscapes of PC offers a more comprehensive understanding and could identif...