Weather conditions are closely related to human health, yet effective methods for communicating the joint health risks associated with weather-related factors remain limited, especially when accounting for the complex interactions among weather expos...
The evolution of biosensors demands synergistic improvements in signal transduction and data processing. We present a universal biosensing platform that combines dual-mode signal responses from silver-modulated gold nanorods (AuNRs) and gold-silver n...
Proceedings of the National Academy of Sciences of the United States of America
Nov 4, 2025
Human neural networks of interconnected neurons have evolved to be remarkably efficient and are capable of learning and memory through the brain's synaptic plasticity, including short-term plasticity (STP), and long-term potentiation (LTP) and depres...
BACKGROUND: Ovarian cancer (OC) demonstrates the poorest prognosis among gynecological malignancies, with five-year survival rates below 45%, primarily due to late-stage diagnosis. To address this challenge, we systematically identified OC-specific d...
OBJECTIVE: To identify the potential diagnostic biomarkers and therapeutic targets of atherosclerotic carotid artery stenosis (ACAS), a comprehensive bioinformatics analysis was conducted to identify its related key genes and regulatory networks.
BACKGROUND: We aim to assess the diagnosis performance of an ensemble machine learning (ML) based radiomic analysis of multiparametric cardiac magnetic resonance (CMR) to differentiate light chain cardiac amyloidosis (AL-CA) and hypertrophic cardiomy...
BMC medical informatics and decision making
Nov 4, 2025
BACKGROUND: Myocardial infarction (MI) is a life-threatening condition caused by sudden interruption of blood supply to the heart. Electrocardiogram (ECG) is the primary tool for MI diagnosis, but interpretation challenges exist. This study aimed to ...
OBJECTIVES: This study aimed to develop and validate a CT radiomics-based explainable machine learning model for precise diagnosing of malignancy and benignity specifically in endometrial cancer (EC) patients.
Cytotoxic T cells (CD8) play a pivotal role in immunosurveillance by identifying and eliminating tumor cells. However, the onset of CD8 T cell exhaustion, characterized by overexpression of immune checkpoint receptors, impairs their function, allowin...
BACKGROUND: Gout is the most common inflammatory arthritis. Recurrent flares are common among hospitalised patients and contribute to substantial clinical and economic burden. However, the accurate prediction of inpatient recurrence remains challengi...
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