Molecularly imprinted polymers (MIPs) have emerged as transformative synthetic receptors for mycotoxin detection, addressing critical global food safety challenges through their exceptional stability and design flexibility. This review systematically...
Cardiovascular disease (CVD) is the top cause of mortality globally, making it crucial to diagnose arrhythmias promptly and accurately for the early prevention and treatment of CVD. While numerous methods exist for detecting arrhythmias using ECG sig...
Foodborne contaminants, such as mycotoxins and microplastics, pose significant threats to human health due to their high toxicity and persistence in the food chain, thus necessitate effective mitigation strategies. Lactic acid bacteria (LAB), charact...
Diabetic kidney disease (DKD) remains a critical challenge in diabetes management, necessitating a deep understanding of its molecular underpinnings for better diagnosis and treatment strategies. This study was conducted to identify and validate nove...
Artificial intelligence (AI) has potential to surpass human capabilities to reshape vaccine design. However, its integration raises legal, ethical, and intellectual property challenges. Transparency in AI-driven immunological products is crucial for ...
European journal of psychotraumatology
Oct 15, 2025
The exponential growth of research literature makes it increasingly difficult to identify all relevant studies for systematic reviews and meta-analyses. While traditional search methods are labour-intensive, modern AI-aided approaches have the poten...
International journal of pharmaceutics
Oct 15, 2025
The ophthalmic route for drug administration remains a significant constraint in ophthalmology due to the unique anatomy and several protective barriers in the eyes, which limit absorption and therapeutic efficacy. Conventionally, drugs are delivered...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Oct 15, 2025
BACKGROUND: Ulcerative colitis (UC) is a chronic, relapsing inflammatory bowel disease with rising prevalence and limited therapies. Zhilining Formula (ZLN), a Traditional Chinese Medicine (TCM), shows clinical efficacy in UC, yet its core material b...
XGBoost, a gradient boosting algorithm, is widely recognized for its efficiency and robustness in multiclass classification tasks. Metabolomics serves as a powerful tool for biomarker discovery; however, metabolic biomarkers associated with the progr...
Many enzymes are vital drug targets in diseases such as cancer and pathogenic infections; however, mutations can drastically disrupt inhibitor binding to confer resistance. Resistance mutations primarily occur at the inhibitor binding site, but accom...
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