AIMC Topic: Humans

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A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML.

Journal of translational medicine
BACKGROUND: Comprehensive analysis of single-cell transcriptome and chromatin accessibility will contribute to interpret the heterogeneity of acute myeloid leukemia (AML). We hypothesize that integrating single-cell transcriptomic and chromatin acces...

Optimized feature selection and advanced machine learning for stroke risk prediction in revascularized coronary artery disease patients.

BMC medical informatics and decision making
BACKGROUND: Coronary artery disease (CAD) remains a leading cause of global mortality, with stroke constituting a significant complication among patients undergoing coronary revascularization procedures, such as percutaneous coronary intervention (PC...

Beyond labels: determining the true type of blood gas samples in ICU patients through supervised machine learning.

BMC medical informatics and decision making
BACKGROUND: In the Intensive Care Unit (ICU), data stored in patient data management systems (PDMS) is commonly used in clinical practice and research. Parameters from point-of-care arterial blood gas (BG) analysis are used in the diagnosis and defin...

Precision nutrition in epigenetic aging: SHAP-optimized machine learning identifies omega-3 constituent-specific associations with aging biomarkers.

Biogerontology
This cross-sectional investigation seeks to examine the association between dietary omega-3 fatty acids (including α-linolenic acid [ALA], eicosapentaenoic acid [EPA], and docosahexaenoic acid [DHA]) and biomarkers of cellular aging, specifically DNA...

Perceived social support in the daily life of people with Parkinson's disease: a distinct role and potential classifier.

Scientific reports
Motor outcomes in Parkinson's disease (PD) have long been the primary diagnostic criteria and treatment targets. While non-motor outcomes of PD impact daily well-being, they are rarely targeted by interventions or utilized for classification. Despite...

Considering the Social and Economic Sustainability of AI.

Science and engineering ethics
In recent years, the notion of 'sustainable AI' has emerged as a new topic within the wider debate on artificial intelligence (AI). Although sustainability is usually understood as having three dimensions - the environment, society, and the economy -...

Wave Propagation Phenomena in Nonlinear Hierarchical Neural Networks with Predictive Coding Feedback Dynamics.

Bulletin of mathematical biology
We propose a mathematical framework to systematically explore the propagation properties of a class of continuous in time nonlinear neural network models comprising a hierarchy of processing areas, mutually connected according to the principles of pr...

Enhanced HER-2 prediction in breast cancer through synergistic integration of deep learning, ultrasound radiomics, and clinical data.

Scientific reports
This study integrates ultrasound Radiomics with clinical data to enhance the diagnostic accuracy of HER-2 expression status in breast cancer, aiming to provide more reliable treatment strategies for this aggressive disease. We included ultrasound ima...

Hybrid deep learning framework based on EfficientViT for classification of gastrointestinal diseases.

Scientific reports
GI diseases are one of the leading causes of morbidity and mortality worldwide, and early and accurate diagnosis is considered to be very important. Traditional methods like endoscopy take time and depend majorly on the judgment of the physician. The...