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Annotating Diseases Using Human Phenotype Ontology Improves Prediction of Disease-Associated Long Non-coding RNAs.

Journal of molecular biology
Recently, many long non-coding RNAs (lncRNAs) have been identified and their biological function has been characterized; however, our understanding of their underlying molecular mechanisms related to disease is still limited. To overcome the limitati...

Microaneurysm Detection Using Principal Component Analysis and Machine Learning Methods.

IEEE transactions on nanobioscience
Diabetic retinopathy (DR) is an eye abnormality caused by long-term diabetes and it is the most common cause of blindness before the age of 50. Microaneurysms (MAs), resulting from leakage from retinal blood vessels, are early indicators of DR. In th...

A Novel Method to Predict Knee Osteoarthritis Progression on MRI Using Machine Learning Methods.

IEEE transactions on nanobioscience
This paper explored the hidden biomedical information from knee magnetic resonance (MR) images for osteoarthritis (OA) prediction. We have computed the cartilage damage index (CDI) information from 36 informative locations on tibiofemoral cartilage c...

Tracking antibiotic resistance gene pollution from different sources using machine-learning classification.

Microbiome
BACKGROUND: Antimicrobial resistance (AMR) has been a worldwide public health concern. Current widespread AMR pollution has posed a big challenge in accurately disentangling source-sink relationship, which has been further confounded by point and non...

Robot-based intervention may reduce delay in the production of intransitive gestures in Chinese-speaking preschoolers with autism spectrum disorder.

Molecular autism
BACKGROUND: Past studies have shown that robot-based intervention was effective in improving gestural use in children with autism spectrum disorders (ASD). The present study examined whether children with ASD could catch up to the level of gestural p...

Concussion classification via deep learning using whole-brain white matter fiber strains.

PloS one
Developing an accurate and reliable injury predictor is central to the biomechanical studies of traumatic brain injury. State-of-the-art efforts continue to rely on empirical, scalar metrics based on kinematics or model-estimated tissue responses exp...

Using Machine Learning to Advance Personality Assessment and Theory.

Personality and social psychology review : an official journal of the Society for Personality and Social Psychology, Inc
Machine learning has led to important advances in society. One of the most exciting applications of machine learning in psychological science has been the development of assessment tools that can powerfully predict human behavior and personality trai...

Integrating spatial-anatomical regularization and structure sparsity into SVM: Improving interpretation of Alzheimer's disease classification.

NeuroImage
In recent years, machine learning approaches have been successfully applied to the field of neuroimaging for classification and regression tasks. However, many approaches do not give an intuitive relation between the raw features and the diagnosis. T...

Computer-assisted liver graft steatosis assessment via learning-based texture analysis.

International journal of computer assisted radiology and surgery
PURPOSE: Fast and accurate graft hepatic steatosis (HS) assessment is of primary importance for lowering liver dysfunction risks after transplantation. Histopathological analysis of biopsied liver is the gold standard for assessing HS, despite being ...

Prediction of central neuropathic pain in spinal cord injury based on EEG classifier.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVES: To create a classifier based on electroencephalography (EEG) to identify spinal cord injured (SCI) participants at risk of developing central neuropathic pain (CNP) by comparing them with patients who had already developed pain and with a...