AIMC Topic: Humans

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Identification of a panel of volatile organic compounds in urine for early detection of for bladder cancer.

Scientific reports
The absence of specific markers makes early detection of bladder cancer (BC) challenging. Recent studies have reported the reliable diagnostic significance of volatile organic compounds (VOCs) in several cancers. This study aimed to investigate wheth...

Intestinal permeability of N-acetylcysteine is driven by gut microbiota-dependent cysteine palmitoylation.

Nature communications
Trillions of intestinal microbiota are essential to the permeability of orally administered drugs. However, identifying microbial-drug interactions remains challenging due to the highly variable composition of intestinal flora among individuals. Usin...

Feasibility study of a general model for synthetic CT generation in MRI-guided extracranial radiotherapy.

Biomedical physics & engineering express
This study aims to investigate the feasibility of a single general model to synthesize CT images across body sites, thorax, abdomen, and pelvis, to support treatment planning for MRI-only radiotherapy. A total of 157 patients who received MRI-guided ...

Flexible iontronic sensing.

Chemical Society reviews
The emerging flexible iontronic sensing (FITS) technology has introduced a novel modality for tactile perception, mimicking the topological structure of human skin while providing a viable strategy for seamless integration with biological systems. Wi...

Use of Large Language Models in Clinical Cancer Research.

JCO clinical cancer informatics
Artificial intelligence (AI) is increasingly being applied to clinical cancer research, driving precision oncology objectives by gathering clinical data at scales that were not previously possible. Although small, domain-specific models have been use...

Development and validation of a nomogram for differentiating immune checkpoint inhibitor-related pneumonitis from pneumonia in patients undergoing immunochemotherapy: a multicenter, real-world, retrospective study.

Frontiers in immunology
BACKGROUND: Immune Checkpoint Inhibitor-related Pneumonitis (CIP) exhibits high morbidity and mortality rates in the real world, often coexisting with pneumonia, particularly after immunochemotherapy. We aimed to develop and validate a non-invasive n...

Study on the relationship between vaginal dose and radiation-induced vaginal injury following cervical cancer radiotherapy, and model development.

Frontiers in public health
OBJECTIVE: This study investigates the relationship between vaginal radiation dose and radiation-induced vaginal injury in cervical cancer patients, with the aim of developing a risk prediction model to support personalized treatment strategies.

[Cluster predictors of trajectories of leisure-time physical activity intensity in men and women from ELSA-Brasil].

Cadernos de saude publica
The maintenance of physical activity over time is a challenge for public health. Predictors of different physical activity intensities have not been sufficiently analyzed. This study aimed to identify clusters of trajectories of physical activity int...

A data-driven scoring framework for personalized employee health check-ups: Integrating historical laboratory trends and evidence-based prevalence.

International journal of medical informatics
INTRODUCTION: Rising healthcare costs and growing demand for personalized preventive care have highlighted the need for data-driven approaches to optimize health check-ups, particularly in corporate settings. This study presents a scoring-based platf...

3D Micro-Expression Recognition Based on Adaptive Dynamic Vision.

Sensors (Basel, Switzerland)
In the research on intelligent perception, dynamic emotion recognition has been the focus in recent years. Small samples and unbalanced data are the main reasons for the low recognition accuracy of current technologies. Inspired by circular convoluti...