AIMC Topic: Immunoglobulin G

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Seroprevalence of antibodies for pertussis and diphtheria among people leaving or entering China: a cross-sectional study.

Journal of infection in developing countries May 31, 2019
INTRODUCTION: Despite high population immunity, pertussis remains one of the leading causes of vaccine-preventable deaths worldwide. The aim of this study was to determine the seroprevalence of IgG antibodies to pertussis toxin (PT) and diphtheria am...
Travel-Related Illness Whooping Cough Africa Adult Antibodies, Bacterial Cross-Sectional Studies China Male Seroepidemiologic Studies Humans Diphtheria Middle Aged Asian People Employment Immunoglobulin G Pertussis Toxin Young Adult
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Rapid Identification of Disulfide Bonds and Cysteine-Related Variants in an IgG1 Knob-into-Hole Bispecific Antibody Enhanced by Machine Learning.

Analytical chemistry Dec 14, 2018
Bispecific antibodies are regarded as the next generation of therapeutic modalities as they can simultaneously bind multiple targets, increasing the efficacy of treatments for several diseases and opening up previously unattainable treatment designs....
Immunoglobulin G Disulfides Cysteine Antibodies, Bispecific Machine Learning
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Novel electrochemical sensing platform based on a nanocomposite of PVA/PVP/RGO applied to IgG anti- Toxoplasma gondii antibodies quantitation.

Talanta Nov 30, 2018
This article describes the development of a new electrochemical platform composed by a polymer mixture and graphene oxide (GO). The working electrode of a screen-printed carbon electrode (SPCE) was modified with nanocomposite constituted by poly-viny...
Povidone Toxoplasma Electrodes Nanocomposites Graphite Antibodies, Protozoan Polyvinyl Alcohol Immunoglobulin G Biosensing Techniques Electrochemical Techniques Oxides Humans
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Dynamic changes in specific anti-L-asparaginase antibodies generation during acute lymphoblastic leukemia treatment.

Pharmacological reports : PR Nov 28, 2018
BACKGROUND: L-asparaginase (L-asp) remains one of the key components of acute lymphoblastic leukemia therapy. Immune reactions to the drug are associated with its diminished activity. The aim of the study was to determine the level of IgM, IgG and Ig...
Immunoglobulin M Female Precursor Cell Lymphoblastic Leukemia-Lymphoma Male Enzyme-Linked Immunosorbent Assay Adolescent Infant Immunoglobulin E Child, Preschool Humans Antineoplastic Agents Antibodies Child Immunoglobulin G Asparaginase Colorimetry
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Haemophilus influenzae type b (Hib) seroprevalence and current epidemiology in England and Wales.

The Journal of infection Dec 28, 2017
INTRODUCTION: The implementation of the Hib conjugate vaccine in the United Kingdom in 1992 resulted in a rapid decline in invasive Hib disease across all age groups. However, a resurgence in 2000-2002 prompted the introduction of additional control ...
Vaccines, Conjugate Haemophilus Infections Haemophilus Vaccines Haemophilus influenzae type b Vaccination Seroepidemiologic Studies United Kingdom Antibodies, Bacterial Immunization, Secondary Wales Risk Factors Male Infant Prevalence Adolescent Cohort Studies Child, Preschool Child Humans Immunoglobulin G Female
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Electron spin resonance spectroscopy for immunoassay using iron oxide nanoparticles as probe.

Analytical and bioanalytical chemistry Dec 26, 2017
With the help of iron oxide nanoparticles, electron spin resonance spectroscopy (ESR) was applied to immunoassay. Iron oxide nanoparticles were used as the ESR probe in order to achieve an amplification of the signal resulting from the large amount o...
Immunoglobulin G Animals Rabbits Nanoparticles Ferric Compounds Limit of Detection Electron Spin Resonance Spectroscopy Immunoassay Sepharose
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Fast and Sensitive Ellipsometry-Based Biosensing.

Sensors (Basel, Switzerland) Dec 22, 2017
In this work, a biosensing method based on in situ, fast, and sensitive measurements of ellipsometric parameters (, ∆) is proposed. Bare silicon wafer substrate is functionalized and used to bind biomolecules in the solution. Coupled with a 45° dual-...
Silicon Immunoglobulin G Biosensing Techniques
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Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel.

Phytochemical analysis : PCA Dec 20, 2017
INTRODUCTION: Paclitaxel (Tax) is a diterpene alkaloid isolated from Taxus species and has proved clinically effective in treating a number of malignancies. Current quantitative analytical methods for Tax such as high-performance liquid chromatograph...
Humans Immunoglobulin G Reproducibility of Results Fluorescent Antibody Technique Taxus Time and Motion Studies Limit of Detection Animals Enzyme-Linked Immunosorbent Assay Rabbits Antineoplastic Agents, Phytogenic Paclitaxel Antibodies, Monoclonal Calibration
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Specific chemiluminescent protocol for dual-site recognition of Streptococcus mutans utilizing strong affinity between teicoplanin and Gram-positive bacteria.

Talanta Nov 6, 2017
A novel dual-site recognition protocol was developed for chemiluminescent (CL) detection of Streptococcus mutans (S. mutans) based on a designed antibiotic-affinity strategy. Teicoplanin, a broad-spectrum antibiotic against Gram-positive bacteria, wa...
Iodobenzenes Cell Wall Teicoplanin Horseradish Peroxidase Magnetite Nanoparticles Humans Bacterial Proteins Luminescent Measurements Luminol Protein Binding Anti-Bacterial Agents Streptococcus mutans Rats Saliva Immunoglobulin G Fresh Water Dipeptides Animals Limit of Detection Milk Hydrogen Peroxide
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Identification of immune correlates of protection in Shigella infection by application of machine learning.

Journal of biomedical informatics Aug 9, 2017
BACKGROUND: Immunologic correlates of protection are important in vaccine development because they give insight into mechanisms of protection, assist in the identification of promising vaccine candidates, and serve as endpoints in bridging clinical v...
Humans Machine Learning Algorithms Immunoglobulin G Logistic Models Models, Biological Dysentery, Bacillary
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