AIMC Topic: In Vitro Techniques
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Nanocomplexes composed of chitosan derivatives and β-Lactoglobulin as a carrier for anthocyanins: Preparation, stability and bioavailability in vitro.
Food research international (Ottawa, Ont.)
Aug 22, 2018
To improve sustained-release property, stability and bioavailability of anthocyanins (ACNs) in vitro, we fabricated the nanocomplexes with chitosan hydrochloride (CHC), carboxymethyl chitosan (CMC) and β-Lactoglobulin (β-Lg). Response surface methodo...
Identification and characterization of the structure-activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum.
Scientific reports
Dec 20, 2017
The adverse effects of Polygonum (P.) multiflorum, including abnormal bilirubin metabolism, are a serious public health issue. As uridine diphosphate (UDP)-glucuronosyltransferase 1A1 (UGT1A1) is the only enzyme responsible for bilirubin metabolism, ...
Procyanidin A2 in the Australian plant Alectryon oleifolius has anthelmintic activity against equine cyathostomins in vitro.
Veterinary parasitology
Nov 21, 2017
There is a need to investigate new methods of controlling cyathostomins in horses due to increasing anthelmintic resistance amongst these parasites. In a previous study we identified the Australian plant Alectryon oleifolius as having anthelmintic ac...
Machine learning-based prediction of adverse drug effects: An example of seizure-inducing compounds.
Journal of pharmacological sciences
Jan 28, 2017
Various biological factors have been implicated in convulsive seizures, involving side effects of drugs. For the preclinical safety assessment of drug development, it is difficult to predict seizure-inducing side effects. Here, we introduced a machin...
Enhancing analysis throughput, sensitivity and specificity in LC/ESI-MS/MS assay of plasma 25-hydroxyvitamin D by derivatization with triplex 4-(4-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione (DAPTAD) isotopologues.
Journal of pharmaceutical and biomedical analysis
Nov 17, 2016
The plasma/serum concentration of 25-hydroxyvitamin D [25(OH)D] is a diagnostic index for vitamin D deficiency/insufficiency, which is associated with a wide range of diseases, such as rickets, cancer and diabetes. We have reported that the derivatiz...
Characterizing the Input-Output Function of the Olfactory-Limbic Pathway in the Guinea Pig.
Computational intelligence and neuroscience
Jul 28, 2015
Nowadays the neuroscientific community is taking more and more advantage of the continuous interaction between engineers and computational neuroscientists in order to develop neuroprostheses aimed at replacing damaged brain areas with artificial devi...
Enhanced needle localization in ultrasound using beam steering and learning-based segmentation.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Jul 6, 2014
Segmentation of needles in ultrasound images remains a challenging problem. In this paper, we introduce a machine learning-based method for needle segmentation in 2D beam-steered ultrasound images. We used a statistical boosting approach to train a p...
Nerve Block
Chickens
Ultrasonography, Interventional
Injections
Animals
Swine
In Vitro Techniques
Imaging, Three-Dimensional
Humans
Image Interpretation, Computer-Assisted
Machine Learning
Pattern Recognition, Automated
Algorithms
Image Enhancement
Reproducibility of Results
Needles
Sensitivity and Specificity
Use of a Novel Artificial Intelligence Tool for Evaluating Primary Stability and Immediate Loading Suitability of Dental Implants: An In Vitro Pilot Study.
The International journal of oral & maxillofacial implants
Aug 29, 2024
PURPOSE: To evaluate the correspondence between output from a new artificial intelligence tool (AIT) and clinician evaluation regarding the immediate loading suitability of dental implants based on insertion torque curves recorded during implant plac...
A cellular platform for the development of synthetic living machines.
Science robotics
Mar 31, 2021
Robot swarms have, to date, been constructed from artificial materials. Motile biological constructs have been created from muscle cells grown on precisely shaped scaffolds. However, the exploitation of emergent self-organization and functional plast...
Ex-vivo antihypertensive and calcium channel blocking activity of Androsace foliosa n-hexane leaves fraction on isolated rabbit aorta.
Pakistan journal of pharmaceutical sciences
Nov 1, 2019
Hypertension is persistent elevation in blood pressure for 3-4 weeks. Estimated global prevalence of hypertension suggested that by the Year 2025 (29%) of adult worldwide are suffering from hypertension (1.56 billion). Hypertension complications are ...
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