AIMC Topic: Lung Injury
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Noninvasive estimation of PaCO from volumetric capnography in animals with injured lungs: an Artificial Intelligence approach.
Journal of clinical monitoring and computing
Dec 26, 2024
To investigate the feasibility of non-invasively estimating the arterial partial pressure of carbon dioxide (PaCO) using a computational Adaptive Neuro-Fuzzy Inference System (ANFIS) model fed by noninvasive volumetric capnography (VCap) parameters. ...
Metabolic profiling of murine radiation-induced lung injury with Raman spectroscopy and comparative machine learning.
The Analyst
May 13, 2024
Radiation-induced lung injury (RILI) is a dose-limiting toxicity for cancer patients receiving thoracic radiotherapy. As such, it is important to characterize metabolic associations with the early and late stages of RILI, namely pneumonitis and pulmo...
Microscopic computed tomography with AI-CNN-powered image analysis: the path to phenotype bleomycin-induced lung injury.
American journal of physiology. Cell physiology
Apr 22, 2024
Bleomycin (BLM)-induced lung injury in mice is a valuable model for investigating the molecular mechanisms that drive inflammation and fibrosis and for evaluating potential therapeutic approaches to treat the disease. Given high variability in the BL...
Ultra-sensitive analysis of exhaled biomarkers in ozone-exposed mice via PAI-TOFMS assisted with machine learning algorithms.
Journal of hazardous materials
Mar 27, 2024
Ground-level ozone ranks sixth among common air pollutants. It worsens lung diseases like asthma, emphysema, and chronic bronchitis. Despite recent attention from researchers, the link between exhaled breath and ozone-induced injury remains poorly un...
Pulmonary contusion: automated deep learning-based quantitative visualization.
Emergency radiology
Jun 15, 2023
PURPOSE: Rapid automated CT volumetry of pulmonary contusion may predict progression to Acute Respiratory Distress Syndrome (ARDS) and help guide early clinical management in at-risk trauma patients. This study aims to train and validate state-of-the...
Assessing the Severity of COVID-19 Lung Injury in Rheumatic Diseases Versus the General Population Using Deep Learning-Derived Chest Radiograph Scores.
Arthritis care & research
Oct 21, 2022
OBJECTIVE: COVID-19 patients with rheumatic disease have a higher risk of mechanical ventilation than the general population. The present study was undertaken to assess lung involvement using a validated deep learning algorithm that extracts a quanti...
Scalable deep learning algorithm to compute percent pulmonary contusion among patients with rib fractures.
The journal of trauma and acute care surgery
Mar 22, 2022
BACKGROUND: Pulmonary contusion exists along a spectrum of severity, yet is commonly binarily classified as present or absent. We aimed to develop a deep learning algorithm to automate percent pulmonary contusion computation and exemplify how transfe...
PEDF, a pleiotropic WTC-LI biomarker: Machine learning biomarker identification and validation.
PLoS computational biology
Jul 21, 2021
Biomarkers predict World Trade Center-Lung Injury (WTC-LI); however, there remains unaddressed multicollinearity in our serum cytokines, chemokines, and high-throughput platform datasets used to phenotype WTC-disease. To address this concern, we used...
Herpes simplex virus in bronchoalveolar lavage fluid of medical intensive care unit patients: Association with lung injury and outcome.
Journal of critical care
Dec 8, 2015
PURPOSE: In intensive care unit (ICU) patients in whom bronchoalveolar lavage fluid (BALF) was analyzed for suspected infectious pulmonary disease, we investigated the association of herpes simplex virus (HSV) in the BALF with lung injury and patient...
Estimation of extravascular lung water using the transpulmonary ultrasound dilution (TPUD) method: a validation study in neonatal lambs.
Journal of clinical monitoring and computing
Nov 12, 2015
Increased extravascular lung water (EVLW) may contribute to respiratory failure in neonates. Accurate measurement of EVLW in these patients is limited due to the lack of bedside methods. The aim of this pilot study was to investigate the reliability ...
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