Journal of computer-aided molecular design
Jul 8, 2025
Mutations in isocitrate dehydrogenase 1 (IDH1) have been widely observed in various tumors, such as gliomas and acute myeloid leukemia, and therefore has become one of the current research focal points. Therefore, it is crucial to find inhibitors tha...
In this work, we proposed a novel inferential procedure assisted by machine learning based adjustment for randomized control trials. The method was developed under the Rosenbaum's framework of exact tests in randomized experiments with covariate adju...
Despite advancements in trauma care, uncontrolled hemorrhage and trauma-induced coagulopathy (TIC) remain the leading causes of preventable deaths after trauma. Understanding the genetic underpinnings and molecular mechanisms of TIC is crucial for de...
The precise diagnosis of heart disease represents a significant obstacle within the medical field, demanding the implementation of advanced diagnostic instruments and methodologies. This article conducts an extensive examination of the efficacy of di...
Keratoconus is a progressive eye disease characterized by the thinning and bulging of the cornea, leading to visual impairment. Early and accurate diagnosis is crucial for effective management and treatment. This study investigates the application of...
This study investigated the impact of alkaline pretreatment on the biomethane yield of Xyris capensis experimentally and computationally using machine-learning (ML)-based techniques. Despite extensive studies on the anaerobic digestion of lignocellul...
World Health Organization (WHO) estimates 17.9 million deaths globally every year due to Cardiovascular Disease or CVD, which includes an array of disorders of the heart and blood vessels, that includes coronary heart disease, cerebrovascular disease...
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlights the importance of monitoring immune responses to guide vaccination strategies. Although neutralizing antibodies (NAbs) have garnered increasing ...
BACKGROUND: Lung cancer (LC) remains a leading cause of cancer-related mortality worldwide, primarily due to late-stage diagnosis and the absence of effective early detection methods.
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