In BriefAuthors of this study analyzed hospital readmissions following laminectomy and developed predictive models to identify readmitted patients with an accuracy >95% when using all variables and >79% when using only predischarge variables. A model...
European journal of cancer (Oxford, England : 1990)
Dec 7, 2018
BACKGROUND: Mutation of the isocitrate dehydrogenase (IDH) gene and co-deletion on chromosome 1p/19q is becoming increasingly relevant for the evaluation of clinical outcome in glioma. Among the imaging parameters, contrast enhancement (CE) in WHO II...
IMPORTANCE: Despite data aggregation and removal of protected health information, there is concern that deidentified physical activity (PA) data collected from wearable devices can be reidentified. Organizations collecting or distributing such data s...
Knowing the catalytic turnover numbers of enzymes is essential for understanding the growth rate, proteome composition, and physiology of organisms, but experimental data on enzyme turnover numbers is sparse and noisy. Here, we demonstrate that machi...
The discovery of peptide substrates for enzymes with exclusive, selective activities is a central goal in chemical biology. In this paper, we develop a hybrid computational and biochemical method to rapidly optimize peptides for specific, orthogonal ...
BMC medical informatics and decision making
Dec 7, 2018
BACKGROUND: Disease named entity recognition (NER) is a fundamental step in information processing of medical texts. However, disease NER involves complex issues such as descriptive modifiers in actual practice. The accurate identification of disease...
BMC medical informatics and decision making
Dec 7, 2018
BACKGROUND: Medication events in clinical settings are significant threats to patient safety. Analyzing and learning from the medication event reports is an important way to prevent the recurrence of these events. Currently, the analysis of medicatio...
BMC medical informatics and decision making
Dec 7, 2018
BACKGROUND: Automated seizure detection from clinical EEG data can reduce the diagnosis time and facilitate targeting treatment for epileptic patients. However, current detection approaches mainly rely on limited features manually designed by domain ...
IEEE journal of biomedical and health informatics
Dec 6, 2018
Alzheimer's disease (AD), as a severe neurodegenerative disease, is now attracting more and more researchers' attention in the healthcare. With the development of magnetic resonance imaging (MRI), the neuroimaging-based longitudinal analysis is gradu...
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